Leveraging data science applications to improve children's environmental health in sub-saharan africa (DICE)
Active Cooperative Agreement Awarded Last action
- Award ID
- U01ES036147
- Recipient
-
University Of Cape Coast UEI MNBXBLJK6CS6
- Awarding agency
-
National Institute of Environmental Health Sciences
National Institutes of Health, Department of Health and Human Services
- Obligated
- $1,233,929
Award facts
- Assistance listing
- 93.310 Trans-NIH Research Support
- Completion date 79% complete
- Originally
- Funding agency
- Office of the Director National Institutes of Health, Department of Health and Human Services
- Place of performance
- Ghana
Award details come from USAspending.gov.
Description
- Abstract
- Poor environmental conditions such as air pollution, and unsafe water and sanitation have been ranked among the top risk factors for disability-adjusted years (DALYS) in children. The highest number of deaths per capita attributable to environmental exposures have been observed in sub-saharan africa (SSA) with the highest disease burden noted among children. The overall goal of the proposed research is to harness data science applications to establish the spatial variability in the impact of ambient PM2.5 exposure on children's health in SSA and further identify the explanatory and moderating factors. The overall goal of the project would be achieved through the following specific aims: (1) establish the spatial variability in the impact of ambient PM2.5 exposure on children's health in SSA, and explore the effect modifying role of neighbourhood greenness and nutrition, (2) estimate ambient PM2.5 exposures at multi-temporal scales by integrating land use regression (LUR) models, high-resolution ground monitoring data, and mobile monitoring data in uganda and ghana, and (3) identify area - (regional, district) and household-level factors that explain the spatial variability in ambient PM2.5 - child health relationship and establish the temporal changes in these exposure risk profiles. The proposed research seeks to create new knowledge and provide evidence on the potential of data science for addressing children's environmental health problems in SSA in alignment with the DSI-africa program. For aim 1, we will leverage data science tools to combine geospatial PM2.5 exposures estimated using satellite remote sensing with data on child undernutrition, acute respiratory infections, and neonatal and infant deaths assembled from several waves of demographic and health survey (DHS) and multiple indicator cluster survey (MICS) data spanning several decades. We will use a spatial random coefficient model set in a bayesian framework to model the spatially varying relationship between ambient PM2.5 and the child health outcomes of interest controlling for individual- and area-level confounders. For aim 2, we would apply machine learning techniques to develop a land use regression (LUR) model for kampala and accra leveraging mobile and fixed monitoring data and compare the models between the two cities under the following data conditions; (1) using only consistent data available in both cities and (2) using city-specific data to derive locally optimized models. We will in addition evaluate transferability of the models from one city to another, and also, identify the most important temporal and spatial predictors in both cities. For aim 3, we will use bayesian profile regression (BPR) and leveraging the same datasets in aim 1 to identify profile clusters that characterize high PM2.5 exposures and determine which exposure profile clusters is associated with increase prevalence of adverse child health outcomes. We would also explore the temporal changes in exposure profiles in the study countries. The findings of the proposed resaerch should help trigger investment in air pollution control as well as policy action for addressing area and household poverty to help improve child health and survival in SSA.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $244,643 | |
| Amendment | $244,643 | |
| Amendment | $244,643 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $0 | |
| Amendment | $250,000 | |
| Original award | $250,000 |
Show all 11
Quick answers
Who received award U01ES036147?
U01ES036147 was awarded to University Of Cape Coast by National Institute of Environmental Health Sciences (National Institutes of Health) on September 12, 2023.
How much is award U01ES036147 worth?
$1,233,929 has been obligated on U01ES036147.
Which agency awarded U01ES036147?
National Institute of Environmental Health Sciences (National Institutes of Health) awarded U01ES036147, with funding from Office of the Director (National Institutes of Health).
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