Cooperative Agreement R43CE003549

The National Institute on Drug Abuse (NIDA) awarded Instanosis Inc., a woman-owned small business in Pennsylvania, a $1,576,513 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to develop a rapid, sensitive, and instrument-free oral fluid fentanyl test. This project aims to create the first FDA-cleared oral fluid fentanyl rapid test that is 10 times more sensitive, has a 5-minute readout time (4 times faster), and requires 100 mL of oral fluid (10 times less volume)...

This Project Grant award from the National Institute of Justice (CFDA 16.560 - National Institute of Justice Research, Evaluation, and Development Project Grants) provides $434,500 to 9 Delta Analytical, LLC to develop two key products: 1) An inexpensive, visually-read testing device that allows rapid identification of fentanyl and other opioids in oral fluid samples, and 2) Environmentally-friendly laboratory confirmation procedures for analyzing the same oral fluid samples. The goal is to...

This Project Grant award from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), is funding the development of a comprehensive fentanyl testing device by Taesun, LLC. The $305,369 award aims to create an integrated device that simplifies the process of fentanyl detection, making it more accessible and user-friendly for use in high-risk environments. The device will combine multiple testing steps, such as crushing, measuring, and...

The National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems awarded a $399,541 Project Grant to the Trustees of Dartmouth College to develop a high-throughput, label-free, and portable sensor that can quantitatively detect multiple illicit drugs including opioids, cocaine, psychostimulants, and methadone in liquid samples such as biofluids. The project aims to create a silver or gold nanoparticle-decorated zinc oxide nanorod coated silica nanofiber matrix...

The National Institute on Drug Abuse (NIDA) awarded a $386,452 Project Grant (CFDA 93.279 - Drug Use and Addiction Research Programs) to Electronic Biosciences, Inc., a small biotechnology company in San Diego, California. The grant supports the development of a rapid fingerstick diagnostic test for opioid and stimulant use disorders. This project aims to address the escalating public health crisis of opioid and stimulant overdose deaths in the United States, which reached over 107,000 in...

This $228,697 National Science Foundation award under the Engineering program (CFDA 47.041) will support the development of an optical biosensor technology to facilitate drug screening and validation efforts. Auctus Biologics, Inc. will utilize a proprietary temperature, pH, and chemically stable protein composed of two fragments that bind with antibody-like affinity and specificity. Over the one-year period ending January 2023, the company will establish the technology's suitability for...

This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Phase I Small Business Innovation Research (SBIR) project grant, awarded to Selight, LLC, aims to develop a rapid diagnostic instrument for assessing the health and viability of chimeric antigen receptor (CAR) T cells prior to their use in cancer immunotherapy. The $304,733 award, effective July 1, 2025 through June 30, 2026, will fund the design, engineering, and prototyping of an optical metabolic...

This Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) provides $399,715 to Rescue Biomedical, LLC to develop and commercialize the Automatic Detection Device (AD2) component of their Automatic Antidote Delivery Device (A2D2). The AD2 is a user-centric wearable device that can automatically detect opioid overdose and alert emergency services, with the goal of reducing opioid overdose-related deaths. The key...

The National Institute of Justice (NIJ) awarded a $319,172 Project Grant under the NIJ Research, Evaluation, and Development Project Grants program (CFDA 16.560) to Research Triangle Institute (RTI International), an independent non-profit research organization. The grant funding will support evaluating the use of direct mass spectrometry technology, specifically the Luxon ion source, to improve the efficiency and capabilities of toxicology laboratories in screening for drugs related to...

This $586,936 Project Grant award from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) supports the development of a low-cost, disposable urine test strip that can rapidly and quantitatively measure substance use disorder (SUD) medication drugs and their metabolites. The award recipient, Vitan-Biotech LLC, will create a point-of-use lateral flow assay (LFA) test strip that leverages innovative signal amplification technology to...