Medical monitoring project (MMP) - the medical monitoring project (MMP) is a key surveillance activity that describes the behavioral and clinical characteristics of people with HIV (PWH) who are in…

The Centers for Disease Control and Prevention awarded a cooperative agreement to the City and County of San Francisco Public Health Department on September 30, 2025, totaling $643,882, obligated in full. The award funds the Medical Monitoring Project (MMP), a case surveillance activity that describes the behavioral and clinical characteristics of people with HIV in and out of care in San Francisco. The MMP uses surveillance-based sampling to supplement core HIV surveillance, generating data on HIV trends, health outcomes for those in and out of care, barriers to care including HIV stigma and social determinants of health, and equitable access to quality HIV care. Data informs local and national MMP estimates and tracks progress toward San Francisco Department of Public Health and CDC benchmarks under the Ending the HIV Epidemic Initiative and the National HIV/AIDS Strategy. Results will guide decision-making on health and wellbeing for persons living and aging with HIV in San Francisco and are intended to be transportable to other jurisdictions nationwide.

The award is made under the HIV Prevention and Surveillance Activities—Health Department Based program (CFDA 93.940) with a period of performance through September 29, 2030. Work is performed in California. San Francisco was an early pilot site for the MMP's case surveillance-based sampling approach and is one of twenty-three national MMP sites.

Medical monitoring project (MMP) - the medical monitoring project (MMP) is a key surveillance activity that describes the behavioral and clinical characteristics of people with HIV (PWH) who are in and out of HIV care in SAN francisco (SF). The SF MMP one of twenty three national MMP sites uses a case surveillance based sampling approach to supplement core HIV surveillances. Data are leveraged to inform local and national MMP estimates on HIV trends improve HIV related health outcomes for those in and out of care and guide local programmatic responses to changes in quality of life over time. Data dissemination is essential to track recovery from the COVID19 epidemic and progress towards benchmarks boldly set by the SF department of public health (sfdph) SF and cdcs ending the HIV epidemic initiative and the national HIV aids strategy. Understanding barriers to care such as HIV stigma social determinants of health and unmet needs is critical to attaining local and national goals. Data will provide context to social disparities in HIV care and supportive services bridging gaps in knowledge and contributing to a larger coordinated response to ending the HIV epidemic. SF MMP is committed to amplifying pwhs experiences and tracking equitable access to quality HIV care particularly important given the recent advancement of long acting injectable antiretroviral therapy art. In the landscape of an evolving syndemic results will guide decision making on all aspects of health and wellbeing for persons living and aging with HIV in SF. Enumerating behavioral and clinical characteristics will generate data driven insights that are also transportable helping refine interventions and informing care delivery for PWH in SF and the united states. Sfdph is positioned to conduct the next MMP cycle successfully SF was one of the first cities selected by the CDC as a case surveillance based sampling pilot site. The MMP team at sfdph has extensive experience sampling and locating and recruiting PWH from the SF HIV case registry and enrolling them in MMP. Boasting institutional MMP knowledge in house HIV expertise and access to sfdph resources and community partners the team is well poised to continue identifying persons in and out of HIV medical care. The team is successful at conducting routine use of HIV surveillance for data to care activities including enrolling PWH in a sfdph linkage and navigation program that establishes initial HIV care and or return to HIV care and collaborating with HIV partner services. Dissemination of MMP data will also help guide clinical and policy decisions informing budget and resource allocation planning as well as support prevention and treatment efforts as part of the CDC RFA PS240047. Implementation of MMP results in real world clinical and social service settings will help estimate the benefits or harms of healthcare options in practice by different groups living with HIV. Combined these data driven insights will contribute to the overall development and successful roll out of evidence based prevention care and treatment responses to end the HIV epidemic.