National Center for HIV/AIDS

The Department of Health and Human Services Centers for Disease Control and Prevention is a civilian sub-agency that administers federal public-health grants, primarily funding disease-surveillance programs, epidemiological research, and health-department operations at state, local, and academic levels.

CDC has obligated $14.26 billion in federal grant funding across 1,396 awards to 463 distinct recipients since 2007. Grant activity averaged 87 to 108 awards per year from 2022 through 2024, declining to 84 awards in 2025; only 1 award has been recorded so far in 2026. The agency structures its grant portfolio almost exclusively around Cooperative Agreements—1,325 awards (95%)—with a smaller share of Project Grants (71 awards, 5%).

Grant recipient concentration is highly fragmented: the top five recipients by award count hold only 9% of recent awards over the last five years, and the top five by federal dollars account for just 5% of recent federal obligated dollars. Indiana Department of Health leads by recent award count with 8 awards worth $43.2 million in federal dollars, followed by Puerto Rico Department of Health (7 awards, $38.1 million) and three recipients tied at 6 awards each—City & County of San Francisco ($63.9 million), Michigan Department of Health and Human Services ($50.2 million), and Emory University ($114.1 million). By federal-dollar volume, Florida Department of Health ranks highest at $220.9 million (5 awards), trailed by City of New York at $218 million (5 awards) and Emory University at $114.1 million (6 awards). The long tail of 458 other recipients spreads remaining funding across public health entities and academic institutions nationwide.

No recent contract awards or contract opportunities are recorded against CDC or its descendant offices in the available source data. No recent contract opportunities are reported.