Cooperative Agreement NU51IP000843

The National Institute of Allergy and Infectious Diseases (NIAID) awarded Orlance, Inc., a woman-owned small business, a $300,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop an enhanced seasonal influenza DNA vaccine. The project aims to combine the advantages of a closely matched seasonal influenza vaccine with a universal influenza vaccine to provide more robust and durable protection, especially for the elderly and immunocompromised...

This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) aims to develop and test a novel intervention to improve routine vaccination of hospitalized children. The $220,000 award to Seattle Children's Hospital will fund a two-year project with the following key components: Engaging hospital stakeholders to co-develop the "Presumptively Initiating Vaccines and...

The University of Missouri System, under a $650,000 project grant from the USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program, is developing safe and effective live attenuated swine influenza vaccines using Newcastle disease virus (NDV) as the vector. The project aims to address the challenges with current swine influenza vaccines, which often fail to provide cross-protection against diverse virus strains. The key products and...

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $230,000 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to the Scripps Research Institute to develop a broad-spectrum influenza vaccine. The goal of the project is to target the neuraminidase (NA) protein, which is engaged by broadly neutralizing antibodies that can provide protection against diverse influenza strains. The research will evaluate recently discovered NA broadly neutralizing...

This Project Grant award of $709,236 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to develop a nanoparticle-based adjuvant formulation containing a TLR7 agonist to overcome immunodominance and induce broad antibody responses against the influenza virus. The primary research goals are to: 1) Determine how the TLR7 nanoparticle adjuvant impacts immunodominance, breadth, and tolerance across...

This $390,942 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to develop a universal influenza vaccine using self-assembled peptide nanoparticles (SAPNs). The key goals are to: Assemble and characterize SAPNs functionalized with highly conserved influenza antigens, including the hemagglutinin stalk (HRHA) and matrix protein 2 ectodomain (4M2E), on the external surface, and...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) provides $183,541 over 5 years to support an investigation of within-household transmission of influenza in low-resource settings. The research, led by a principal investigator at Yale University, aims to quantify influenza spread within households and develop a model to evaluate the effectiveness of interventions like...

This $1,164,930 Project Grant award from the National Institute on Minority Health and Health Disparities (CFDA 93.307 - Minority Health and Health Disparities Research) will fund a study to examine the impact of school-located vaccination (SLV) models on routine, influenza, and COVID-19 vaccine uptake among school-aged children in Colorado, with a focus on health disparity populations. The prime awardee, The RAND Corporation, will apply quasi-experimental methods, microsimulation modeling,...

This $2,065,719 federal Project Grant award from the National Institute on Minority Health and Health Disparities (CFDA 93.307 - Minority Health and Health Disparities Research) supports a community-based intervention to increase COVID-19 and influenza vaccination rates among African American/Black and Latino (AABL) populations in New York. The primary goal is to identify the most cost-effective combination of intervention components, including nurse-led shared decision making, text message...

The U.S. Department of Agriculture's National Institute of Food and Agriculture (USDA-NIFA) awarded a $9.5M project grant under the Extension Collaborative on Immunization Teaching & Engagement (EXCITE) program to the Extension Foundation. This grant, spanning from Sep 2024 to May 2027, aims to stabilize and increase routine immunization rates in rural and underserved communities. The key objectives are to: 1) increase public confidence in adult vaccinations through collaboration with...