Cooperative Agreement NU2GGH002222

This Cooperative Agreement award from the U.S. Agency for International Development (USAID) under the Foreign Assistance for Programs Overseas (CFDA 98.001) program is intended to scale up and improve the management of drug-resistant tuberculosis (DR-TB) in USAID-supported countries. The $287,878,180 award, with a project period from October 1, 2024 to September 30, 2029, will focus on expanding access to high-quality DR-TB treatment services and providing specialized technical assistance to...

This $550,000 Cooperative Agreement, awarded by the Centers for Disease Control and Prevention (CDC) under the Global Tuberculosis (TB): Developing, Evaluating, Implementing Evidence-based and Innovative Approaches to Find, Cure, and Prevent Tuberculosis Globally program (CFDA 93.494), is funding a five-year collaboration between the CDC and the Union Internationale Contre la Tuberculose et les Maladies Respiratoires (Uitmr), an international non-profit organization based in Paris, France. The...

This federal Cooperative Agreement award, valued at $4,650,276 and granted by the U.S. Agency for International Development (USAID) under the Foreign Assistance for Programs Overseas (CFDA 98.001) program, aims to reduce the tuberculosis (TB) burden and establish a sustainable and responsive care system in Kyrgyzstan. The primary awardee, JSI Research & Training Institute Inc., will lead efforts focused on early screening, diagnosis, personalized treatment, and patient support across...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,350,312 to the University of California, Los Angeles (UCLA) to design and develop a rapid phenotypic drug susceptibility test, termed TRE-DST, for tuberculosis (TB). The TRE-DST system utilizes novel fluorescent trehalose probes to specifically detect live Mycobacterium tuberculosis (MTB) and determine drug...

This Project Grant award from the John E. Fogarty International Center (CFDA 93.989 - International Research and Research Training) provides $108,237 to Mbarara University of Science and Technology in Uganda to develop and assess the feasibility of a diagnostic tool for post-tuberculosis (TB) lung disease that can be deployed in primary healthcare settings. The key objectives are to: (1) create and validate a clinical diagnostic algorithm for post-TB lung disease, (2) conduct qualitative...

This Project Grant award of $1,011,348 from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to understand how interactions between Mycobacterium tuberculosis (M.TB) and the human alveolar environment, particularly in people living with HIV, impact the early stages of TB infection. The key objectives are to: 1) Determine how M.TB exposure to alveolar lining fluid from people living with...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $817,405.00 to Colorado State University and its subrecipient, the University of Tennessee Health Science Center, to develop new drug regimens for treating tuberculosis (TB), including both drug-sensitive and multidrug-resistant strains. The key objectives are to: 1) manufacture and characterize inhalable dry...

The Desmond Tutu Health Foundation received a $790,803 Project Grant from the National Institute of Allergy and Infectious Diseases within the Department of Health and Human Services. The grant supports the foundation's work to develop a method for gathering real-time data on factors influencing tuberculosis treatment adherence among men in South Africa. Specifically, the foundation will integrate modified ecological momentary assessments with medication event monitoring systems and assess the...

This Project Grant award, totaling $559,341, was provided by the Fogarty International Center (FIC), part of the U.S. Department of Health and Human Services National Institutes of Health, under the International Research and Research Training program (CFDA 93.989). The award supports research to improve detection and treatment of tuberculosis (TB) in children under five years old in Malawi. Specifically, the project will: Evaluate the accuracy of new non-invasive TB diagnostic strategies...

This Project Grant award, with Federal Grant ID R03HD113830, was provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865). The $212,636 award, effective September 1, 2024 through August 31, 2026, will support the development of tools to facilitate preventive therapy for children and adolescents exposed to tuberculosis (TB) in primary care settings in low- and middle-income countries....