Center for Global Health

The Centers for Disease Control and Prevention, a sub-agency of the Department of Health and Human Services, administers federal grants to support disease surveillance, prevention research, and global health initiatives. CDC grant-making focuses on public health infrastructure, epidemiological studies, and international partnerships to combat infectious and chronic diseases.

CDC has obligated $34.39 billion in federal grant funding across 1,227 awards since 2006, with 558 distinct recipients. Annual award volume has declined substantially in recent years: 68 awards in 2022, 76 in 2023, 62 in 2024, 9 in 2025, and 2 year-to-date in 2026. The most recent grant award was issued on September 1, 2026.

Grant recipient concentration is highly fragmented over the last five years. The top five recipients by award count account for 11 percent of recent awards, while the top five by federal dollars obligated represent 6 percent of recent federal dollars. The Trustees of Columbia University in the City of New York leads by award count with 9 awards totaling $465.1 million in federal dollars obligated. Institute of Human Virology NIG Ltdgte holds the largest federal commitment by dollars, with 2 awards totaling $562.1 million. Other significant recent recipients include Apin Public Health Initiatives LTD / GTE ($455.6 million across 2 awards), Right To Care ($348.1 million across 2 awards), ZIM - Ttech ($319.2 million across 3 awards), Cameroon Baptist Convention Health Board ($75.5 million across 5 awards), Elizabeth Glaser Pediatric Aids Foundation ($288.8 million across 3 awards), and Georgetown University ($115.5 million across 3 awards).

Nearly all CDC grant funding flows through Cooperative Agreements, which represent 98 percent of awards. Project Grants account for 2 percent, and Block Grants comprise less than 1 percent of the portfolio. The combined total dollars obligated (including non-federal cost-share) reached $35.3 billion across all recipients.

No recent contract awards or opportunities are recorded against CDC in the source data. Grant-making activity has contracted sharply in 2025 and 2026 relative to the prior three-year baseline, warranting clarification on whether this reflects portfolio gaps, temporary reporting delays, or shifted funding priorities before committing resources to pursue new opportunities at the agency.