Gynecologic cancer-center of excellence (GYN-COE) core

This $8.58 million cooperative agreement from the Department of Defense's Uniformed Services University Medical Research Projects program (CFDA 12.750) supports the Gynecologic Cancer Center of Excellence (GYN-COE) Core from April 2021 through April 2023. The GYN-COE aims to identify molecular alterations in gynecologic cancers and develop novel strategies for prevention, early detection, and precision treatment through investigating carcinogenesis and drug resistance in pre-clinical and clinical biospecimens; developing and deploying clinical biomarkers and assays; improving clinical care through evaluation of novel therapeutics and clinical trials; collaborating on investigations of disparities, risk, and treatment; and utilizing military and civilian resources to advance applied proteogenomics and ensure readiness and improved outcomes.

The award supports a tissue and data acquisition network involving subawards to Duke University, the University of Virginia, the University of Oklahoma Health Sciences Center, Ohio State University, and Inova Fairfax Hospital to facilitate specimen and data collection to support future research studies through protocol participation and multidisciplinary collaboration. Principal investigators at the subaward institutions will oversee local execution of the tissue banking protocol and collaborative research initiatives.