Block Grant U50CI024410

The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $1,171,832 Cooperative Agreement under the Allergy and Infectious Diseases Research program (CFDA 93.855) to Emory University. The project, titled "Influenza Modeling of Correlates of Protection for Optimal Immune Dynamics and Evolution," aims to leverage multi-omic data and systems biology modeling to identify novel immune correlates of protection against influenza beyond neutralizing antibodies. The award...

The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a 5-year, $1,082,429 Cooperative Agreement to Duke University to develop multiscale computational models that predict the effectiveness of influenza vaccines. The project, titled "Multiscale Modeling of Influenza Neutralizing Antibody and Fc Effector Biology," aims to address the challenges of seasonal influenza vaccines being only 10-60% effective and providing limited protection against pandemic strains....

This $2,074,701 five-year federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support a multidisciplinary research program at Emory University to study the biological and physical drivers of influenza A virus transmission in humans. The key objectives of the research are to: Define the dynamics of viral load, immune responses, and infectious aerosol production in humans...

The federal Cooperative Agreement award, with ID U01IP001257, was granted by the National Center for Immunization and Respiratory Diseases (NCIRD), a division of the Centers for Disease Control and Prevention (CDC). The $18,893,037 award, spanning from August 1, 2024 to July 31, 2029, supports a "Prospective Observational Study of Respiratory Virus Epidemiology in the Greater Boston Area" under the CDC's "Strengthening Public Health through Surveillance, Epidemiologic Research,...

This $1,225,986 Cooperative Agreement awarded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will support a study to investigate the factors that shape the strength, durability, and breadth of the adaptive immune response to influenza vaccination. The researchers at the University of Chicago will conduct a randomized, placebo-controlled trial to identify individuals with strong versus weaker B and T...

This $600,000 project grant awarded by the National Science Foundation (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program aims to enhance influenza forecasting through an integrated platform for user-generated temporal forecasts. The project takes a participatory modeling approach to guide the construction of a human judgment platform that generates temporal forecasts of infectious disease trajectories. The key goals are to: 1) identify the factors and decision-making...

This Cooperative Agreement award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $1,195,056 to Vanderbilt University to develop and implement computational tools that leverage machine learning to design broadly protective influenza vaccines. The project aims to explore three key immunogen design strategies: 1) germline-targeting on the hemagglutinin lateral patch, 2) hemagglutinin...

This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to advance knowledge on factors that influence the efficiency of influenza A virus (IAV) infection and transmission. The $146,922 award to Emory University will support research to examine how the mode of exposure (direct contact, self-inoculation, or airborne transmission) and environmental conditions (temperature,...

The Indiana State Poultry Association has been awarded a $205,344 Cooperative Agreement from the United States Department of Agriculture (USDA) Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care federal grant program (CFDA 10.025). The purpose of this 1-year agreement is for the association to conduct national surveillance and response activities for avian health, including active and passive surveillance sampling for avian...

This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) will provide $183,541 to Yale University to investigate within-household transmission of influenza in low-resource settings. The overarching goals are to quantify the spread of influenza within households and develop a transmission model to project the effectiveness of interventions like vaccination and masking in...