Purchase Order HU000124P0004

This firm fixed-price purchase order was awarded by the National Institute of Child Health and Human Development (NICHD), part of the Department of Health and Human Services, to Applied Stemcell, Inc. for the generation of a conditional knockout mouse model using CRISPR/Cas9 gene editing technology. The award amount is $26,065.00, and the period of performance runs through July 19, 2021. The contract does not have a set-aside designation. Applied Stemcell is a minority-owned, woman-owned small...

This firm fixed-price purchase order for $18,204.88 was awarded by the Department of Health and Human Services' National Institutes of Health National Institute on Drug Abuse to Genscript USA Inc. to obtain cell lines utilizing CRISPR gene editing technology. Specifically, the contract calls for Genscript to generate knockout HEK293 and HepG2 cell lines of the MMAB and MUT genes to support studies for hereditary disorders of vitamin B12 and methylmalonic acid metabolism. No set-aside designation...

This contract was awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Institute on Drug Abuse to Applied Stemcell, Inc., a minority-owned, woman-owned small business, for a firm-fixed-price purchase order in the amount of $63,000.00. The contract calls for the use of CRISPR gene editing technology to create two custom induced pluripotent stem cell (iPSC) reporter cell lines - one with dual gene knock-ins for albumin and alpha-fetoprotein, and...

The National Institutes of Health's National Center for Advancing Translational Sciences awarded a $356,221 firm fixed price purchase order to Synthego Corporation, located in Redwood City, California. Synthego will deliver one Whole Human Genome Arrayed CRISPR Screening Library to the National Institutes of Health campus in Rockville, Maryland by September 3, 2021. The library, as requested in the solicitation, will contain up to three chemically modified synthetic sgRNAs per well targeting...

The Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases awarded a $25,000 firm fixed price purchase order to Cyagen Biomodels LLC for a project to conditionally knockout mouse WNK1 and STK10 genes using CRISPR/Cas9 technology. Work will be performed by Cyagen Biomodels LLC Division in Santa Clara, California over a period of four months concluding in late December 2023. The award was made to the prime contractor Cyagen...

The Department of Health and Human Services National Institutes of Health National Heart Lung and Blood Institute awarded a $996,710 firm fixed price purchase order to Lumicks USA Inc. to generate HBB, HBBS, and HBBE knock-in mice. The solicitation sought a contractor capable of generating transgenic and knock-in mouse models using CRISPR/Cas9 or other genome editing technologies for biomedical research purposes. No set-aside designation or incumbent contractor was specified. Lumicks will...

The Department of Health and Human Services' National Institutes of Health National Institute of Child Health and Human Development awarded a $121,347 firm fixed price purchase order to Cyagen Biomodels LLC of Santa Clara, California. The contract is for the generation of conditional knock-in and knock-out mouse models to support the agency's research focusing on the development of the mammalian hematopoietic system and study of signal transduction molecules and pathways that regulate T...

This federal contract award to Applied Stemcell, Inc. (a minority owned, woman owned small business) was made by the National Institute of Child Health and Human Development (NICHD), a civilian agency, on August 11, 2019. The $12,639.00 firm fixed price purchase order is for "KNOCKOUT CELL CLONE RASD1" services. Through this award, Applied Stemcell has provided gene editing services to generate customized cell and animal models, including knockout mouse models, reporter cell lines, and...

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $15,000 firm-fixed price purchase order to Applied Stemcell, Inc. to provide gene editing services to generate a conditional knockout mouse model using CRISPR/Cas9 technology. The contract is not set-aside. Applied Stemcell is a minority-owned, woman-owned small business that has previously provided gene editing services to NIDDK, NIAID, NICHD, and NIA under federal contracts and grants. The purchase order was...

Genscript USA Inc. has been awarded a $16,317 firm fixed price purchase order by the National Institutes of Health's National Institute of Allergy and Infectious Diseases to provide genomic editing knock-in services in support of the agency's GENCRISPR program. The contract calls for Genscript to deliver CRISPR/Cas9 gene editing services for the NIH's research on infectious diseases from its facility in Piscataway, New Jersey over a six-month period concluding in late February 2024. No...