Metabolomic analysis of the effects of phenylbutyrate (PB) in patients with myalgic encephalomyelitis/chronic fatigue syndrome (me/CFS)

Active Purchase Order Awarded Last action

Contract number
75N98026P01474
Awardee
Awarding agency
Obligated
$41,400

Award facts

Opportunity
Contract value 100% obligated
$41,400.00 Current and potential, with all options
Completion date 8% complete
Current and potential, with all options
Funding agency
National Heart Lung and Blood Institute National Institutes of Health, Department of Health and Human Services
NAICS code
621511 Medical Laboratories
PSC
Q301 Reference Laboratory Testing
Set-aside
No set-aside
Competition
Not Competed · 1 offer Only One Source
Pricing
Firm Fixed Price
Place of performance
Morrisville, NC, USA

Award details come from SAM.gov/FPDS.

About this award

The National Heart, Lung and Blood Institute awarded a purchase order to Metabolon, Inc. valued at $41,400 on September 30, 2026 for metabolomic analysis of phenylbutyrate effects in myalgic encephalomyelitis/chronic fatigue syndrome patients.

Work is performed in Morrisville, North Carolina. The order calls for untargeted metabolomic profiling and bioinformatic analysis of 75 plasma samples from 30 ME/CFS patients at baseline and after eight weeks of sodium phenylbutyrate treatment, plus 15 healthy control samples. Metabolon will conduct three comparative analyses: baseline ME/CFS versus healthy controls, post-treatment versus baseline ME/CFS, and post-treatment ME/CFS versus healthy controls. The base performance period runs from September 30, 2026 through September 29, 2027. This procurement was non-competitive, justified by the requirement for analytical continuity with Metabolon's existing ME/CFS dataset to avoid methodological variability and preserve scientific validity.

Quick answers

Who was awarded contract 75N98026P01474?

75N98026P01474 was awarded to Metabolon, Inc. by Office of Logisitics and Acquisition Operations (National Institutes of Health) on September 30, 2026.

How much is contract 75N98026P01474 worth?

The government has obligated $41,400 on 75N98026P01474.

Which agency awarded contract 75N98026P01474?

Office of Logisitics and Acquisition Operations (National Institutes of Health) awarded 75N98026P01474, with funding from National Heart Lung and Blood Institute (National Institutes of Health).

Was contract 75N98026P01474 competed?

The extent of competition for 75N98026P01474 was not competed. The government received 1 offer.

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