Purchase Order 75N95024P00430
- Not listed
- This firm-fixed-price purchase order contract was awarded by the National Institute on Drug Abuse, a civilian agency within the U.S. Department of Health and Human Services, to Insphero Inc., a foreign-owned, for-profit manufacturer of advanced 3D cell culture technologies. The $46,829.63 contract tasks Insphero with providing 3D liver microtissues composed of human primary hepatocytes and other liver cells, which are used for drug-induced liver injury assays and toxicity testing. These...
- The National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services, has awarded a $96,829.63 firm-fixed-price purchase order to Insphero Inc., a foreign-owned, for-profit manufacturer of 3D cell culture technologies. The contract is for a Transcriptomics study - RNA-seq in Liver Spheroids Phase One, with the purpose of evaluating the safety and liver toxicity of candidate antisense oligonucleotides using a 3D liver microtissue...
- The National Center for Advancing Translational Sciences (NCATS), a civilian agency within the U.S. Department of Health and Human Services, awarded a $75,000.00 firm-fixed-price purchase order to Insphero Inc., a foreign-owned for-profit manufacturer of advanced 3D cell culture products. The contract is for safety assessment studies using Insphero's human, mouse, and rat 3D liver spheroid models to evaluate drug-induced liver injury (DILI) as part of the DILIPLUS assay program. This contract...
- Insphero, Inc. has been awarded a firm fixed price purchase order valued at twenty-two thousand eight hundred dollars from the Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences. The contract calls for Insphero to provide 3D liver microtissues composed of human primary hepatocytes and liver cells for drug testing and safety assessments. Insphero will deliver the 3D liver spheroids to support drug-induced liver injury assays...
- This purchase order contract was awarded by the National Institutes of Health's National Center for Advancing Translational Sciences to Life Technologies Corporation for the delivery of 50 vials of human spheroid-qualified hepatocytes. As described in the original solicitation, these liver cells will support the National Institute on Drug Abuse's Antiviral Program for Pandemics by enabling the continued identification of direct-acting antivirals and development of microphysiological systems...
- This is a firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency within the U.S. Department of Health and Human Services, to Life Technologies Corporation, a manufacturer of scientific instruments, reagents, and consumables. The $24,262.29 contract is for the delivery of primary human hepatocytes, which are a critical reagent used in biomedical research supported by NCATS. This contract is not associated with any set-aside...
- The Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences (NCATS) awarded a $150,000.00 firm fixed-price purchase order to 3Dnamics Inc., a biotechnology company, for services related to the differentiation and characterization of induced pluripotent stem cell (iPSC) lines. This non-competitive commercial item acquisition was conducted under simplified acquisition procedures without a small business set-aside. The services...
- This is a firm fixed-price purchase order contract awarded by the National Center for Advancing Translational Sciences (NCATS), a component of the Department of Health and Human Services (HHS), to Mimetas Operations US, Co., a foreign-owned, self-certified small disadvantaged business. The $150,480.00 contract is for the acquisition of Organoplate Grafts, which are microfluidic 3D cell culture plates used in scientific research projects related to SARS-CoV-2 and COVID-19. This contract was...
- The Department of Health and Human Services' National Institutes of Health National Center for Advancing Translational Sciences (NIH NCATS) awarded a $122,612.40 firm fixed-price purchase order to Horizon Discovery Biosciences LIMITED, a foreign-owned for-profit manufacturer, for 14 Mouse ON-TARGET plus small interfering RNA (siRNA) libraries. This non-competitive, brand-name acquisition was conducted under simplified acquisition procedures without any small business set-aside. The purchase...
- This is a $24,900 firm-fixed-price purchase order awarded by the Department of Health and Human Services' National Institutes of Health (NIH) National Center for Advancing Translational Sciences to 3Dnamics Inc., a biotechnology company that provides stem cell engineering technology and related services. The contract is for the differentiation of induced pluripotent stem cells (iPSCs) into hepatocyte organoids, which are three-dimensional cell cultures that model liver tissue. This work supports...
This is a $90,414 firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), a civilian agency within the Department of Health and Human Services, to Insphero Inc., a foreign-owned, for-profit manufacturer of 3D cell culture technologies and in vitro models. The contract is for a Liver Assay in Liver Spheroids to evaluate the toxicity of short interfering RNA (siRNA) and antisense oligonucleotides (ASOs), which are increasingly being used as individualized medicines. The objective is to generate proof-of-concept data using a 3D liver microtissue platform to predict the safety of future candidate siRNA/ASOs intended for clinical use. This is a non-competitive acquisition conducted under simplified acquisition procedures, with no set-aside designation. The period of performance is approximately 12 weeks from the award date of July 29, 2024.
Name | Description | Solicitation Number | FederalAgency | Type | PostedDate |
|---|---|---|---|---|---|
Liver Assay in Liver Spheroids for siRNA/ASOs | 75N95024Q00441 | Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse | Solicitation 1/1 | 7/16/24, 2:35 PM |
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | Not listed | $90.4k | 7/26/24 |