Brand Name or Equal Waters Semi-preparative high-performance liquid chromatography system with mass spectrometry detector
Awarded contract 75N95022P00405 to Waters Technologies Corporation for 244125.71 on 2022-08-10. 75N95022Q00278 Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse
8/22/22, 1:01 PM Brand Name or Equal Waters Semi-preparative high-performance liquid chromatography system with mass spectrometry detector
COMBINED SYNOPSIS / SOLICITATION BRAND NAME OR EQUAL Title: Brand Name or Equal Waters Waters AutoPurification System with SQD2 MS Detector (i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N95022Q00278 and the solicitation is issued as a Request for Quote (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; and FAR Part 12—Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition teshold. This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; FAR Subpart 13.5— Simplified Procedures for Certain Commercial Items; and FAR Part 12—Acquisition of Commercial Items, and is expected to exceed the simplified acquisition teshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect tough Federal Acquisition Circular (FAC) Number 2022-06, with effective date May 26, 2022. (iv) The associated NAICS code 334516 – Analytical Laboratory Instrument Manufacturing and the small business size standard is 1,000 employees. (v) Set-aside Status: Not set aside for Small Business Concerns (vi) Competition Status: This requirement is posted as competitive Generic Name of Product: Semi-preparative high-performance liquid comatography system with mass spectrometry detector Purchase Description: Waters AutoPurification System with SQD2 MS Detector Salient characteristics: The unique features of the Waters AutoPurification System with SQD2 MS Detector 1. 176804203 - Waters AutoPurification System With the following configuration: a. 176003182 - AutoPurification Core System w/SFO b. 176002670 - SQD2 MS c. 176002685 - Vac Rough Pump + Freq Conv d. 700002741 - ACQUITY / Quattro micro or Quattro Premier MS Start-up Solution Kit e. 700006006 - Xevo TQD Standard Kit f. 716000765 - Fractionlynx Dye kit g. 716000261 - STANDARD FRACTION LYNX h. 176002998 - 2998 Photodiode Array Detector i. 205000439 - Splitter, Flow, 5000:1, 30-100mL j. 176001064 - FractionLynx k. 176001303 - ML Standard PC for AutoPurification l. 668000273 - MONITOR, 23" m. WAT207000 - ASSY, HPLC PUMP, M515 n. 205000108 - KIT, 27X7 13 MM TUBE INJ RACK o. 205000117 - KIT 2767 16MM FRACTION COLLECTOR RACK p. 741000322 - FRACTIONLYNX MS INSTALLATION CERT q. 741000520 - System Disposal-Customer r. 750000491 - NA - On-Site Autopur Trg Ed Cert (3days) 2. 720002242EN - Implementation Kit (vii) The Government anticipates award of a firm fixed-price purchase order for this acquisition, and the anticipated delivery date is Thirty days after receipt of order (ARO). Delivery will be f.o.b. destination. The place of delivery and acceptance will be 9800 Medical Center Drive, Building B, Rockville, MD 20850. (viii) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html (End of provision) The following provisions apply to this acquisition and are incorporated by reference: • FAR 52.204-7, System for Award Management (Oct 2018) • FAR 52.204-16, Commercial and Government Entity Code Reporting (Aug 2020) • FAR 52.212-1, Instructions to Offerors-Commercial Items (Nov 2021) • FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (May 2022) • FAR 52.225-2, Buy American Certificate (Feb 2021) • FAR 52.225-4, Buy American-Free Trade Agreements-Israel Trade Act Certificate (Feb 2021) • 52.212-5 attachment, then also include Alternate I, II, or III (May 2022) • FAR 52.225-6, Trade Agreements Certificate (Feb 2021) • HHSAR 352.239-73, Electronic and Information Technology Accessibility Notice (December 18, 2015) The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html The following clauses apply to this acquisition and are incorporated by reference: • FAR 52.204-13, System for Award Management Maintenance (Oct 2018) • FAR 52.204-18, Commercial and Government Entity Code Maintenance (Aug 2020) • FAR 52.212-4, Contract Terms and Conditions--Commercial Items (Nov 2021). Addendum to this FAR clause applies to this acquisition and is attached. • HHSAR 352.239-74, Electronic and Information Technology Accessibility (December 18, 2015) • HHSAR 352.232-71 Electronic Submission of Payment Requests (Feb 2022) • FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders--Commercial Items (May 2022) • NIH Invoice and Payment Provisions (Feb 2021) • FAR 52.211-6, Brand Name or Equal (Aug 1999) • FAR 52.219-6 Notice of Total Small Business Set-Aside (Nov 2020) EVALUATION (ix) The Government may perform a comparative evaluation of responses in accordance with FAR 13.106-2(b) to select the contractor that is best suited and provides the best value, considering the evaluation factors in this solicitation. The evaluation will compare: Technical capability of the item offered to meet the Government requirement in accordance with the salient characteristics specified in the Purchase Description, Price, and Past Performance as defined under FAR 13.106-2(b)(3). If only one quotation is received it will be evaluated on the preceding. The government reserves the right to select a response that provides benefit to the government that exceeds the minimum; the government is not required to select a response that exceeds the minimum; responses may exceed the requirements; each response must meet the solicitation requirement statement at a minimum; and the government is not requesting or accepting alternate proposal(s). (x) The Offerors to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications-Commercial Items (Nov 2021), with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer. (xi) The clause at FAR 52.212-4, Contract Terms and Conditions-Commercial Items (Nov 2021), applies to this acquisition. Addendum to this FAR clause applies to this acquisition and is attached. (xii) The following additional contract requirement(s) or terms and conditions as determined by the contracting officer are necessary for this acquisition and consistent with customary commercial practices. (xiii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. SUBMISSION INSTRUCTIONS (xiv) Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product or service. The price quote shall include unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s), product description, and any other information or factors that may be considered in the award decision. Such factors may include: past performance, special features required for effective program performance, trade-in considerations, probable life of the item selected as compared with that of a comparable item, warranty considerations, maintenance availability, and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order The Unique Entity ID from SAM.gov, UEI Number, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must submit a Buy American Certificate with their quote. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All questions must be received by 11:00 a.m., EST, on July 12, 2022, and reference Solicitation Number 75N95022Q00278. Questions may be submitted electronically to Michelle Cecilia, Contracting Officer, at michelle.cecilia@nih.gov. All quotations must be received by 3:00 p.m., EST, on July 21, 2022, and reference Solicitation Number 75N95022Q00278. Responses must be submitted electronically to Michelle Cecilia, Contracting Officer, at Michelle.cecilia@nih.gov. Fax responses will not be accepted. (xv) The name and telephone number of the individual to contact for information regarding the solicitation: Michelle Cecilia Contract Officer Phone: (301) 827-7199 Email: michelle.cecilia@nih.gov ATTACHMENTS • Purchase Description • FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes Executive Orders–Commercial Items (Jan 2022) • NIH Invoice and Payment Provisions (Feb 2021) • FAR 52.212-4_Addendum_Supplier_Licenses Revised: February 10, 2021 • FAR 52.225-2 Buy American Certificate (Feb 2021) 75N95022Q00278 Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse
7/7/22, 5:36 PM Semi-preparative high-performance liquid chromatography system with mass spectrometry detector
SAM.gov SOURCES SOUGHT NOTICE COVID-19 1. Solicitation Number: 75N95022Q00278 2. Title: Semi-preparative high-performance liquid comatography system with mass spectrometry detector 3. Classification Code: 6640 – Instruments and Laboratory Equipment 4. NAICS Code: 334516 – Analytical Laboratory Instrument Manufacturing 5. Size Standard: 1,000 6. Description: This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: NCATS has become a key partner in the Antiviral Program for Pandemics (APP), a multi-agency initiative that includes NIAID and BARDA, to accelerate antiviral development tough early discovery and preclinical development of safe and effective oral antivirals. The initial priority for the APP is to develop treatments for SARS-CoV-2 and other coronaviruses, with the program expanding to address other virus families with pandemic potential. NCATS will apply its proficiency in drug discovery and development and its cutting-edge technologies to fill critical needs of the APP, such as (i) target validation, (ii) high-toughput screening (HTS) for drug starting points, (iii) medicinal chemistry for lead optimization, and (iv) preclinical, investigational new drug (IND)-enabling development. APP chemists within DPI are tasked with the discovery and development potential small molecule antiviral treatments for a range of viruses that have pandemic potential. In order to meet the increased demand for sample purification and analysis, the Analytical Chemistry Core (ACC) needs to improve toughput and expand capabilities tough procurement of additional instrumentation and equipment, as well as the application of new technologies. Purpose and Objectives: The ACC provides analytical chemistry services involving the isolation, purification, identification, and analysis of therapeutic modalities for targeted disease states. This is accomplished tough the development and usage of the SMART Centralized Sample Purification and Processing Platform. This workflow employs both Gilson and Waters semi-preparative liquid comatography systems with a selection of preparative columns capable of purifying a wide range of small molecules and peptides. The Gilson platform utilizes UV-directed sample collection while the Waters platform employs both UV- and mass-directed detection and collection. The current Gilson purification system in the Bldg A Chemistry lab is over 10 yrs old and has been experiencing more severe malfunctions with increasing frequency. This has contributed to a greater backlog of samples and a decrease in productivity. The obsolete instrument needs to be replaced due to the increased service needs, longer down times, and an observed reduction in product recovery amounts. As such, the ACC requires the acquisition of a replacement purification system, specifically a Waters AutoPurification System with SQD2 MS Detector, which is the same Waters instrument employed in the Bldg C Chemistry lab. By utilizing the same instrumentation across all labs, we enable greater standardization and efficiency of the SMART Centralized Sample Purification and Processing Platform. Additionally, the redundancy of Waters AutoPurification systems will provide increased consistency with purification results, as well as allow better cross-coverage due to instrument familiarity by the comatography chemists. The new purification system will provide higher robustness, greater performance, and increased capabilities for the purification of compounds synthesized by APP, ETB, TDB, and CGB medicinal chemists within DPI. Project requirements: Waters ACQUITY UltraPerformance C2 SFC instrument with QDa– Brand name or similar The unique features of the Waters AutoPurification System with SQD2 MS Detector are: 1. 176804203 - Waters AutoPurification System With the following configuration: a. 176003182 - AutoPurification Core System w/SFO b. 176002670 - SQD2 MS c. 176002685 - Vac Rough Pump + Freq Conv d. 700002741 - ACQUITY / Quattro micro or Quattro Premier MS Start-up Solution Kit e. 700006006 - Xevo TQD Standard Kit f. 716000765 - Fractionlynx Dye kit g. 716000261 - STANDARD FRACTION LYNX h. 176002998 - 2998 Photodiode Array Detector i. 205000439 - Splitter, Flow, 5000:1, 30-100mL j. 176001064 - FractionLynx k. 176001303 - ML Standard PC for AutoPurification l. 668000273 - MONITOR, 23" m. WAT207000 - ASSY, HPLC PUMP, M515 n. 205000108 - KIT, 27X7 13 MM TUBE INJ RACK o. 205000117 - KIT 2767 16MM FRACTION COLLECTOR RACK p. 741000322 - FRACTIONLYNX MS INSTALLATION CERT q. 741000520 - System Disposal-Customer r. 750000491 - NA - On-Site Autopur Trg Ed Cert (3days) 2. 720002242EN - Implementation Kit Two (2) of item# 1m and one (1) each of the other products listed in salient characteristics. Anticipated period of performance: Product must have a 12-month manufacturer’s warranty to begin upon instrument installation. Delivery – Thirty days ARO. Other important considerations: Cite any other information that is necessary for potential respondents to understand the nature of the potential requirement or proposed acquisition. In case domestic sources are available and capable of fulfilling the Government’s need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25. Capability statement /information sought. Small business concerns that believe they possess the capabilities to provide the required products should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Small businesses must also provide their Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. Interested small businesses are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. The respondent must also provide their Unique Entity ID from SAM.gov, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc., pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing. The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to Michelle Cecilia, Contracting Officer at e-mail address michelle.cecilia@nih.gov and must include the Solicitation Number 75N95022Q00278. The response must be received on or before June 6, 2022, at 3:00 p.m., Eastern Time. “Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).” 75N95022Q00278 Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse
5/27/22, 2:41 PM