Purchase Order 75N95021P00420

This is a $107,700.00 firm fixed-price purchase order awarded by the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health, to Curia Global Inc. (doing business as Amri) for cGMP mitragynine HCl supplemental stability and analytical activities. The work supports the preclinical development of mitragynine as part of NCATS' Helping to End Addiction Long-term (HEAL) initiative. Curia, a leading contract development and manufacturing organization,...

<p>The National Center for Advancing Translational Sciences awarded a purchase order to Govage, Inc. for $18,091.92 on September 30, 2020. The order procures 100 milligrams of CAS 442898-34-2, a chemical compound, with firm fixed pricing and an ultimate completion date of December 31, 2020. Performance occurs at Govage's location in Hazelwood, Missouri. Govage is a small, minority-owned business certified as a small disadvantaged business and women-owned small business.</p>

This firm fixed-price contract for $80,300 was awarded by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences to Affinity Research Chemicals Inc. of Stanton, Delaware. The contract calls for the delivery of 5 kilograms of non-GMP grade methyl 4-(((5-phenylpyrazin-2-yl)methyl)carbamoyl)benzoate, a key intermediate and regulatory starting material required for further process development and cGMP manufacture of the...

This is a $36,000.00 firm fixed-price contract awarded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which is part of the National Institutes of Health (NIH), a civilian agency. The contract was awarded to Entrechem SL, a for-profit manufacturer located in Spain, to provide 100g each of two specialized chemical compounds, (1S,2S)-trans-N-Boc-Tetrahydro-3,4-furandiamine and (1R,2R)-trans-N-Boc-Tetrahydro-3,4-furandiamine. These compounds are needed as starting...

This is a firm fixed-price purchase order awarded by the Department of Health and Human Services National Institutes of Health National Center for Advancing Translational Sciences to A1 Biochem Labs LLC, a small business, for the purchase of 34 intermediate chemical compounds in 5g quantities with purity greater than 95%. The total potential value of the award is $112,350.00. This requirement was set aside for total small business participation and is part of the agency's Coronavirus COVID-19...

This firm fixed price purchase order awards Enamine LTD $230,323.60 to provide the National Center for Advancing Translational Sciences two general GPCR libraries totaling 27,000 compounds at $5.20 per compound. The libraries will support the National Institutes of Health's National Institute on Drug Abuse in identifying and developing novel small molecule leads against human disease targets through screening of thousands of compounds. One library will contain a minimum of 25,000 general GPCR...

The National Center for Advancing Translational Sciences (NCATS) awarded a purchase order to Karebay Biochem Inc. for $38,600 on May 11, 2026, to provide calibration services for analytical instruments. Work is performed in Rockville, Maryland. The order covers synthesis of two specialized JAK2 inhibitor compounds at 95% purity, confirmed by NMR and LCMS analysis, for brain cancer cell assays: 10 grams of...

<p>The National Human Genome Research Institute awarded a purchase order to Pine Pharmaceuticals LLC for compendial testing of various pills, valued at $14,700.00, on May 29, 2020. Work is performed in Tonawanda, New York. The order is firm fixed price with an ultimate completion date of June 26, 2020.</p>

This is a delivery order awarded by the National Institute on Drug Abuse (part of the National Institutes of Health under the Department of Health and Human Services) to Bachem Americas, Inc., a foreign-owned for-profit manufacturer of pharmaceutical ingredients. The $1,050,039.90 firm fixed-price contract is for the manufacture of 200 grams of current Good Manufacturing Practice (cGMP) parathyroid hormone-related protein (PTH-rP). The work is being conducted under the parent &quot;CRO Support...

The National Institute on Drug Abuse awarded a $101,000 firm fixed-price purchase order to Chemogenics Biopharma, LLC on September 16, 2025, for synthesis and bioanalytical analysis services supporting the National Center for Advancing Translational Sciences (NCATS) Early Translational Branch Chemistry Program. The contract, which extends through July 15, 2026, is performable in Durham, North Carolina. This procurement does not utilize a small business set-aside designation. The work involves...