The non-GMP synthesis of 100 grams of (r)-n-(6-chloro-4-((1-phenylethyl)amino)pyrido[3,4-d]pyrimidin-5-YL)methane-sulfonamide (MTX-531)

Ended Awarded Last action

Contract number
75N91022F00002
Awardee
Awarding agency
Obligated
$42,941

Award facts

Contract value 100% obligated
$42,941.42 Current and potential, with all options
Completion date 100% complete
Current and potential, with all options
PSC
6810 Chemicals
Set-aside
Total Small Business
Competition
Full and Open Competition after exclusion of sources Negotiated Proposal / Quote
Pricing
Cost Plus Fixed Fee
Place of performance
Santa Fe, FL 32615, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action P00001 · 2026 UDO initiative -$946
Original award $43,888

About this award

The National Cancer Institute awarded a $42,941.42 delivery order to Alchem Laboratories Corporation for the non-Good Manufacturing Practice (non-GMP) synthesis of 100 grams of (R)-N-(6-chloro-4-((1-phenylethyl)amino)pyrido[3,4-d]pyrimidin-5-yl)methanesulfonamide (MTX-531), a small molecule compound. The contract was awarded on July 22, 2022, with an ultimate completion date of October 21, 2022, under a cost-plus-fixed-fee pricing structure. This award was designated as a Total Small Business set-aside and is part of the 2026 UDO Initiative. Performance will be conducted at Alchem's facility in Alachua, Florida.

Alchem Laboratories Corporation is a custom research organization specializing in organic synthesis and pharmaceutical manufacturing services. The company has an established relationship with the National Cancer Institute, operating under a $12 million indefinite delivery vehicle through 2028 for synthesis and analysis of both GMP and non-GMP bulk drugs and pharmaceutical formulations. This delivery order represents a focused task to provide a specific research compound to support the Institute's cancer research program.

Quick answers

Who was awarded contract 75N91022F00002?

75N91022F00002 was awarded to Alchem Laboratories Corporation by National Cancer Institute (National Institutes of Health) on July 22, 2022.

How much is contract 75N91022F00002 worth?

The government has obligated $42,941 on 75N91022F00002.

Is contract 75N91022F00002 an order under another contract?

Yes. 75N91022F00002 is a delivery order under HHSN261201700007I, an indefinite delivery contract.

Was contract 75N91022F00002 competed?

The extent of competition for 75N91022F00002 was full and open competition after exclusion of sources. It was set aside: Total Small Business.

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