Targeting STAT3 to prevent colorectal cancer secondary to inflammatory bowel disease

Ended Awarded Last action

Contract number
75N91021F00002
Awardee
Awarding agency
Obligated
$930,247

Award facts

Contract value 100% obligated
$930,247.00 Current and potential, with all options
Completion date 100% complete
  • Current, with exercised options
  • Potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 1 offer Multiple Award, Fair Opportunity
Pricing
Firm Fixed Price
Place of performance
Houston, TX 77030, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00007 -$2,701
Supplemental Agreement for work within scope P00006 $0
Supplemental Agreement for work within scope P00005 $0
Supplemental Agreement for work within scope P00004 $0
Supplemental Agreement for work within scope P00003 $0
Other Administrative Action P00002 · Base contract title: prevent preclinical drug development program: preclinical efficacy & intermediate biomarkers task order title: targeting STAT3 to prevent… $0
Other Administrative Action P00001 $0
Original award $932,948

About this award

The University of Texas MD Anderson Cancer Center received a $930,247 firm fixed-price delivery order from the National Cancer Institute to conduct preclinical research targeting STAT3 as a mechanism to prevent colorectal cancer in patients with inflammatory bowel disease. Awarded on September 16, 2021, with an ultimate completion date of September 15, 2025, this delivery order falls under the PREVENT Preclinical Drug Development Program, a comprehensive National Cancer Institute initiative designed to advance cancer prevention through systematic preclinical efficacy testing and biomarker evaluation. The work will be performed at MD Anderson's Houston, Texas facility. The contract was not designated as a small business set-aside, reflecting MD Anderson's status as a premier academic research institution with substantial competitive capabilities in federal contracting.

This delivery order is issued under the PREVENT Cancer Preclinical Drug Development Program IDC, a $149.995 billion multiple-award Indefinite Delivery/Indefinite Quantity vehicle that enables the National Cancer Institute to issue task orders for cancer preventive agent development across various contractors. MD Anderson, as a child entity of the University of Texas System, has demonstrated extensive expertise in executing complex preclinical drug development contracts for federal agencies. The specific focus on STAT3 inhibition reflects the National Cancer Institute's strategic emphasis on identifying novel molecular targets and biomarkers that can interrupt inflammatory pathways underlying cancer development, particularly in high-risk populations with inflammatory bowel disease.

Quick answers

Who was awarded contract 75N91021F00002?

75N91021F00002 was awarded to The Univeristy Of Texas M.d. Anderson Cancer Center by National Cancer Institute (National Institutes of Health) on September 16, 2021.

How much is contract 75N91021F00002 worth?

The government has obligated $930,247 on 75N91021F00002.

Is contract 75N91021F00002 an order under another contract?

Yes. 75N91021F00002 is a delivery order under 75N91019D00021, an indefinite delivery contract, on PREVENT Preclinical Drug Development Program (PREVENT).

Was contract 75N91021F00002 competed?

The extent of competition for 75N91021F00002 was full and open competition. The government received 1 offer.

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