Bioengineer long-lasting 3D neurovascular microphysiological system to model chronic inflammation-mediated neurodegeneration
Active Definitive Contract Awarded Last action
- Contract number
- 80ARC023CA005
- Awardee
-
Northeastern University UEI HLTMVS2JZBS6 Part of The Commonwealth Of Massachusetts
- Awarding agency
-
Ames Research Center
National Aeronautics and Space Administration
- Obligated
- $1,998,311
Award facts
- Opportunity
-
- NASA Research Announcement (NRA): Extended Longevity of 3D Tissues and Microphysiological Systems for Modeling of Acute and Chronic Exposures to Stressors Solicitation · NNH21ZDA015N · Posted May 27, 2021
- Contract value 100% obligated
- $1,998,311.00 Current and potential, with all options
- Completion date 92% complete
- Current and potential, with all options
- Contracting staff
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Set-aside
- No set-aside
- Competition
- Full and Open Competition · 9 offers Basic Research
- Pricing
- Firm Fixed Price
- Place of performance
- Boston, MA 02115, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Supplemental Agreement for work within scope | $0 | |
| Funding Only Action | $250,000 | |
| Supplemental Agreement for work within scope | $0 | |
| Funding Only Action | $250,000 | |
| Change Order | $0 | |
| Funding Only Action | $248,311 | |
| Funding Only Action | $500,000 | |
| Funding Only Action | $250,000 | |
| Original award | $500,000 |
About this award
NASA Ames Research Center awarded a $1.998 million definitive contract to Northeastern University for bioengineering a long-lasting 3D neurovascular microphysiological system to model chronic inflammation-mediated neurodegeneration on February 21, 2023, with a firm fixed-price structure and no set-aside.
The contract extends through February 20, 2027. The originating solicitation, posted May 27, 2021, sought proposals from eligible organizations under NAICS 541715 to develop 3D tissues and microphysiological systems with extended longevity of at least six months to model acute and chronic stressor exposures. The multi-agency research announcement from NASA, NIH, HHS BARDA, and FDA anticipated distributing $12 to 20 million across 6 to 10 awards of up to $2 million each over four years. Place of performance is Boston, MA 02115.
Icahn School of Medicine at Mount Sinai provides human ES cells carrying the H2BGFP reporter and generates microglia and other cell types derived from human ES cells, in addition to supporting experimental design and interpretation of data related to inflammation-mediated neurodegeneration.
In FY2023, Northeastern invoiced $209 thousand across 1.0 FTEs and 2,095 contractor hours, yielding a derived government-paid rate of $99.91 per hour. The prime self-performed all reported hours with no subcontractor labor reported under SCI thresholds in that fiscal year.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Icahn School Of Medicine At Mount Sinai | $49,719 | |
| Icahn School Of Medicine At Mount Sinai | $50,000 | |
| Icahn School Of Medicine At Mount Sinai | $49,179 | |
| Icahn School Of Medicine At Mount Sinai | $150,000 |
Quick answers
Who was awarded contract 80ARC023CA005?
80ARC023CA005 was awarded to Northeastern University by Ames Research Center (National Aeronautics and Space Administration) on February 21, 2023.
How much is contract 80ARC023CA005 worth?
The government has obligated $1,998,311 on 80ARC023CA005.
Was contract 80ARC023CA005 competed?
The extent of competition for 80ARC023CA005 was full and open competition. The government received 9 offers.
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