Long-lived single- and multi-organ tissue equivalent (OTE) platforms to model the response of human tissues to various stressors
Active Definitive Contract Awarded Last action
- Contract number
- 80ARC022CA008
- Awardee
-
Wake Forest University Health Sciences UEI SN7KD2UK7GC5 Part of Wake Forest University
- Awarding agency
-
Ames Research Center
National Aeronautics and Space Administration
- Obligated
- $1,997,816
Award facts
- Opportunity
-
- NASA Research Announcement (NRA): Extended Longevity of 3D Tissues and Microphysiological Systems for Modeling of Acute and Chronic Exposures to Stressors Solicitation · NNH21ZDA015N · Posted May 27, 2021
- Contract value 100% obligated
- $1,997,816.35 Current and potential, with all options
- Completion date 81% complete
- Current and potential, with all options
- Contracting staff
- NAICS code
- 541715 Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
- Set-aside
- No set-aside
- Competition
- Full and Open Competition · 9 offers Basic Research
- Pricing
- Firm Fixed Price
- Place of performance
- Winston-Salem, NC 27157, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Supplemental Agreement for work within scope | $0 | |
| Other Administrative Action | $0 | |
| Funding Only Action | $507,432 | |
| Definitize Change Order | $0 | |
| Other Administrative Action | $0 | |
| Funding Only Action | $509,615 | |
| Modification | $500,000 | |
| Other Administrative Action | $0 | |
| Funding Only Action | $480,769 |
About this award
NASA Ames Research Center awarded a $1,997,816 definitive contract to Wake Forest University Health Sciences for development of long-lived single- and multi-organ tissue equivalent platforms to model human tissue response to various stressors, with award date September 29, 2022 and ultimate completion September 29, 2027.
The originating solicitation, posted May 27, 2021, sought proposals from eligible non-governmental organizations to develop 3D tissues and microphysiological systems with extended longevity of at least six months to model acute and chronic exposures to stressors. The multi-agency effort, coordinated by NASA, NIH, HHS BARDA, and FDA, anticipated total funding of $12–20 million across 6 to 10 principal investigator-led awards of up to $2 million over four years. Work is performed in Winston-Salem, NC.
Brigham & Women's Hospital Inc., Department of Faulkner Pathology, serves as a subcontractor, contributing expertise in cell death sensors and bioanalytical integration for the multi-organ-on-chip system. The subcontract was awarded September 22, 2025, and focuses on microfluidic integration of biosensors to monitor microenvironmental parameters, cellular metabolism, and soluble biomarkers secreted from organ-on-chip systems.
The contract carries firm fixed price terms.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Brigham & Womens Hospital Inc. | $74,999 |
Quick answers
Who was awarded contract 80ARC022CA008?
80ARC022CA008 was awarded to Wake Forest University Health Sciences by Ames Research Center (National Aeronautics and Space Administration) on September 29, 2022.
How much is contract 80ARC022CA008 worth?
The government has obligated $1,997,816 on 80ARC022CA008.
Was contract 80ARC022CA008 competed?
The extent of competition for 80ARC022CA008 was full and open competition. The government received 9 offers.
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