Modeling anthracycline-triggered vascular dysfunction

Active Definitive Contract Awarded Last action

Contract number
80ARC022CA007
Awardee
Awarding agency
Obligated
$1,999,512

Award facts

Contract value 100% obligated
$1,999,512.00 Current and potential, with all options
Completion date 82% complete
Current and potential, with all options
Contracting staff
Set-aside
No set-aside
Competition
Full and Open Competition · 9 offers Basic Research
Pricing
Firm Fixed Price
Place of performance
Boston, MA 02115, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00010 $0
Other Administrative Action P00009 · Bioengineer long-lasting 3D neurovascular microphysiological system to model chronic inflammation-mediated neurodegeneration $0
Funding Only Action P00008 $499,512
Other Administrative Action P00007 $0
Other Administrative Action P00006 $0
Other Administrative Action P00005 $0
Other Administrative Action P00004 $0
Funding Only Action P00002 $500,000
Definitize Change Order P00001 $0
Funding Only Action P00003 · 3D tissue chip contract $500,000
Original award $500,000
Show all 11

About this award

NASA Ames Research Center awarded a $2 million definitive contract to Brigham & Women's Hospital Inc. for development of long-lasting 3D neurovascular microphysiological systems to model chronic inflammation-mediated neurodegeneration and anthracycline-triggered vascular dysfunction on September 27, 2022, with an ultimate completion date of September 26, 2027.

The originating NASA-NIH-BARDA-FDA research announcement, posted May 27, 2021, sought proposals to develop 3D tissues and microphysiological systems with extended longevity of at least six months to model acute and chronic exposures to stressors. This award represents one of 6 to 10 principal investigator-led contracts funded across the multi-agency effort at up to $2 million per award over four years. Place of performance is Boston, MA.

The contract is priced firm fixed price. The Charles Stark Draper Laboratory, Inc., a non-profit research and development organization, provides engineering and vascular model expertise, including PREDICT96 hardware to extend vascular model longevity and study chemotherapeutic impacts on vascular health.

Government-invoiced labor in FY2023 totaled $500 thousand across 1,804 contractor hours and 0.9 FTEs, representing a derived government-paid hourly rate of $277.09 per hour. The prime self-performed all reported hours with no subcontractor labor invoiced.

Subawards

Subcontractor Amount Awarded
The Charles Stark Draper Laboratory, Inc. 3D TISSUE CHIP CONTRACT Draper will be providing engineering and vascular model expertise as well as PREDICT96 hardware to enable BWH to conduct the research… $679,321

Quick answers

Who was awarded contract 80ARC022CA007?

80ARC022CA007 was awarded to Brigham & Womens Hospital Inc. by Ames Research Center (National Aeronautics and Space Administration) on September 27, 2022.

How much is contract 80ARC022CA007 worth?

The government has obligated $1,999,512 on 80ARC022CA007.

Was contract 80ARC022CA007 competed?

The extent of competition for 80ARC022CA007 was full and open competition. The government received 9 offers.

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