E014398. CD4 and CD8 T cell epitopes recognized in autoimmune and autoinflammatory diseases
Active Definitive Contract Awarded Last action
- Contract number
- 75N93024C00085
- Awardee
-
University Of Massachusetts Medical School UEI MQE2JHHJW9Q8
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $3,420,000
Award facts
- Opportunity
-
- Large-scale T cell immune epitope discovery and mechanisms of T cell protection Pre-Solicitation · 75N93022R00023 · Posted Mar 6, 2023
- Contract value 59% obligated
-
- $3,420,000.00 Current, with exercised options
- $5,820,000.00 Potential, with all options
- Completion date 53% complete
-
- Current, with exercised options
- Potential, with all options
- NAICS code
- 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Set-aside
- No set-aside
- Competition
- Full and Open Competition · 12 offers Negotiated Proposal / Quote
- Pricing
- Cost No Fee
- Place of performance
- Worcester, MA 01605, USA
- Legislative mandates
-
- Employment Eligibility Verification (E-Verify) FAR subpart 22.18
- Service Contract Inventory FAR subpart 4.17
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Supplemental Agreement for work within scope | $1,200,000 | |
| Change Order | $1,020,000 | |
| Other Administrative Action | $0 | |
| Original award | $1,200,000 |
About this award
The National Institute of Allergy and Infectious Diseases awarded a $5.82 million definitive contract to University of Massachusetts Medical School for CD4 and CD8 T cell epitopes recognized in autoimmune and autoinflammatory diseases on September 30, 2024, under cost-reimbursement, no-fee pricing with no set-aside.
The originating solicitation, posted March 6, 2023, sought proposals for multi-disciplinary research teams to conduct large-scale discovery and validation of T cell immune epitopes associated with infectious diseases, autoimmune diseases, commensal organisms, or alloantigens influencing transplant outcomes. Investigators were also invited to develop or refine T cell epitope prediction tools. Place of performance is Worcester, MA. The ultimate completion date is September 29, 2028.
In FY2025, the contract invoiced $878 thousand across 4.2 FTEs and 8,764 contractor hours, at a derived government-paid rate of $100.23 per hour. Subcontractors performed 43 percent of contractor hours. Columbia University Medical School provides subject recruitment and tissue isolation from amyotrophic lateral sclerosis and control subjects for single-cell RNA and TCR sequencing, with samples processed and shipped to the Stern laboratory at UMass for MHC peptidome analysis. Weill Medical College of Cornell University performs MHC elution and identification of eluted peptides toward discovery of novel autoimmune and inflammatory disease epitopes.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| The Trustees Of Columbia University In The City Of New York | $333,000 | |
| Weill Medical College Of Cornell University | $231,968 |
Quick answers
Who was awarded contract 75N93024C00085?
75N93024C00085 was awarded to University Of Massachusetts Medical School by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 30, 2024.
How much is contract 75N93024C00085 worth?
The government has obligated $3,420,000 on 75N93024C00085. Its potential value, with all options, is $5,820,000.
Was contract 75N93024C00085 competed?
The extent of competition for 75N93024C00085 was full and open competition. The government received 12 offers.
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