Development of saponin dmlt adjuvant (SDA)

Active Definitive Contract Awarded Last action

Contract number
75N93023C00045
Awardee
Awarding agency
Obligated
$6,697,750

Award facts

Opportunity
  • 75N93022R00009 Solicitation number
Contract value 100% obligated
$6,697,749.97 Current and potential, with all options
Completion date 62% complete
  • Current, with exercised options
  • Potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 24 offers Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
New Orleans, LA 70112, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Exercise an Option P00005 · EO14398; "development of saponin dmlt adjuvant (SDA)" $2,002,363
Funding Only Action P00004 · FY26 UDO initiative: EOI::EO: radical transparency about wasteful spending: EOI bilateral modification to descope for FY2025 cost savings: "development of… -$0
Other Administrative Action P00003 · EOI::EO: radical transparency about wasteful spending: EOI bilateral modification to descope for FY2025 cost savings: "development of saponin dmlt adjuvant… $1,493,832
Other Administrative Action P00002 $0
Exercise an Option P00001 $1,598,870
Original award $1,602,685

About this award

The National Institute of Allergy and Infectious Diseases awarded a $6.7 million firm fixed price definitive contract to The Administrators Of Tulane Educational Fund, doing business as Tulane University, for development of saponin DMLT adjuvant on September 30, 2023, with performance completion by September 29, 2028.

The contract funds preclinical development of combination adjuvants for oral vaccine delivery, spanning saponin adjuvant characterization and purification, dual-potency evaluation methods, and pre-IND regulatory preparation. Work is performed in New Orleans, Louisiana.

Tulane engages three named subcontractors: Q-Vant Biosciences, Inc. provides Type-2 grade saponins and QS-21 adjuvants across development milestones; Path A Washington Nonprofit Corp supports combination adjuvant formulation for oral delivery; and The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. generates recombinant ETEC and Campylobacter jejuni antigens, provides bacterial strains, and delivers hands-on technical training for small animal model development and immunogenicity studies.

Service Contract Inventory data for this contract shows 6.3 FTEs and 13,173 contractor hours invoiced in FY2025, with a blended government-paid hourly rate of $142.48/hr. FY2024 invoiced $1 million across 7.3 FTEs at $67.01/hr, reflecting year-over-year rate escalation.

Subawards

Subcontractor Amount Awarded
Q-Vant Biosciences, Inc. DEVELOPMENT OF SAPONIN DMLT ADJUVANT (SDA) Q-Vant Biosciences, Inc. will be a key partner by providing all the Saponin adjuvants for these studies and by… $381,249
Path DEVELOPMENT OF SAPONIN DMLT ADJUVANT (SDA) Path's proposed scope of work under this subcontract is to support the development of combination adjuvants Saponin… $305,854
Path DEVELOPMENT OF SAPONIN DMLT ADJUVANT (SDA) PATH's proposed scope of work under this subcontract to Tulane University is to support the development of… $313,194
Q-Vant Biosciences, Inc. DEVELOPMENT OF SAPONIN DMLT ADJUVANT (SDA) Q-Vant will be a key partner by providing all the Saponin adjuvant for combination in these studies. This includes… $231,969
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. DEVELOPMENT OF SAPONIN DMLT ADJUVANT (SDA) Generation of recombinant adhesin-pillin Enterotoxigenic Escherichia coli (ETEC) antigens HJF will produce,… $256,034

Quick answers

Who was awarded contract 75N93023C00045?

75N93023C00045 was awarded to The Administrators Of Tulane Educational Fund by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 30, 2023.

How much is contract 75N93023C00045 worth?

The government has obligated $6,697,750 on 75N93023C00045.

Was contract 75N93023C00045 competed?

The extent of competition for 75N93023C00045 was full and open competition. The government received 24 offers.

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