Adjuvant comparison and characterization

Active Definitive Contract Awarded Last action

Contract number
75N93022C00053
Awardee
Awarding agency
Obligated
$8,457,032

Award facts

Opportunity
Contract value 100% obligated
$8,457,032.00 Current and potential, with all options
Completion date 74% complete
Current and potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 10 offers Negotiated Proposal / Quote
Pricing
Cost No Fee
Place of performance
Durham, NC 27710, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00015 $0
Other Administrative Action P00014 $0
Other Administrative Action P00013 · EO 14398 - adjuvant comparison and characterization $0
Change Order P00012 $1,699,307
Change Order P00011 · EOI:: implementing the presidents department of government efficiency cost efficiency initiative (march 19, 2025)::EOI modification to descope adjuvant… $934,999
Other Administrative Action P00010 $0
Supplemental Agreement for work within scope P00009 $0
Change Order P00008 $796,466
Change Order P00007 $306,758
Other Administrative Action P00006 $0
Exercise an Option P00005 $1,099,999
Change Order P00004 $500,000
Exercise an Option P00003 $1,099,999
Change Order P00002 $722,690
Change Order P00001 $196,814
Original award $1,100,000
Show all 16

About this award

The National Institute of Allergy and Infectious Diseases awarded an $8.457 million definitive contract to Duke University for adjuvant comparison and characterization on September 1, 2022, under a cost-no-fee pricing structure with no set-aside.

The originating pre-solicitation, posted March 10, 2021, describes a multi-award program to compare adjuvants using vaccine and antigen platforms through comprehensive immune assessments, including omics and functional assays to establish immunological profiles of adjuvant strength, quality, breadth, and durability. Duke's scope includes developing and manufacturing formulations for test adjuvants, conducting in vitro assays, and performing in vivo immunogenicity studies, with performance through the university's Office of Research Administration Division in Durham, NC.

The contract runs through April 30, 2028. Subcontractors include Inimmune Corp, which supplies formulated adjuvant compounds and participates in biweekly project coordination, and the University of North Carolina at Chapel Hill, which performs in vivo mouse studies, human peripheral blood cell assays, and omics analysis on samples shipped from Duke.

Duke's SCI reporting shows actual government-invoiced labor of $734 thousand in FY2023 (2.7 FTEs, 5,610 contractor hours at $130.81 per hour), $1.8 million in FY2024 (1.1 FTEs, 2,323 contractor hours at $788.00 per hour), and $1.4 million in FY2025 (6.7 FTEs). Duke self-performed all reported hours across the measurement period with no subcontractor labor reported under SCI.

Subawards

Subcontractor Amount Awarded
Inimmune Corp ADJUVANT COMPARISON AND CHARACTERIZATION 2.1 Activity (RA-2A): The Contractor shall provide the equipment, facilities, and other resources required to develop… $613,590
University Of North Carolina At Chapel Hill ADJUVANT COMPARISON AND CHARACTERIZATION The overall goal of this project is to evaluate various adjuvants and combinations of these adjuvants for use in… $600,846

Quick answers

Who was awarded contract 75N93022C00053?

75N93022C00053 was awarded to Duke University by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 1, 2022.

How much is contract 75N93022C00053 worth?

The government has obligated $8,457,032 on 75N93022C00053.

Was contract 75N93022C00053 competed?

The extent of competition for 75N93022C00053 was full and open competition. The government received 10 offers.

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