To identify novel adjuvant candidates that can be used to augment the efficacy of human vaccines.
Ended Definitive Contract Awarded Last action
- Contract number
- 75N93019C00041
- Awardee
-
The University Of Chicago UEI ZUE9HKT2CLC9
- Awarding agency
-
National Institute of Allergy and Infectious Diseases
National Institutes of Health, Department of Health and Human Services
- Obligated
- $9,981,722
Award facts
- Opportunity
-
- Vaccine Adjuvant Discovery Program Pre-Solicitation · NIAIDDAITNIHAI201700100 · Posted Jan 17, 2018
- Vaccine Adjuvant Discovery Program Award Notice · Posted Feb 2, 2018
- Contract value 100% obligated
- $9,981,721.80 Current and potential, with all options
- Completion date 100% complete
- Current and potential, with all options
- NAICS code
- 541714 Research and Development in Biotechnology (except Nanobiotechnology)
- Set-aside
- No set-aside
- Competition
- Full and Open Competition · 12 offers Negotiated Proposal / Quote
- Pricing
- Cost No Fee
- Place of performance
- Chicago, IL 60637, USA
Award details come from SAM.gov/FPDS.
Transactions
| Action | Obligated | Date |
|---|---|---|
| Funding Only Action | -$1,746 | |
| Change Order | $1,027,798 | |
| Funding Only Action | -$66 | |
| Other Administrative Action | $0 | |
| Exercise an Option | $1,449,134 | |
| Other Administrative Action | $0 | |
| Exercise an Option | $1,387,684 | |
| Other Administrative Action | $0 | |
| Other Administrative Action | $0 | |
| Other Administrative Action | $0 | |
| Other Administrative Action | $0 | |
| Exercise an Option | $1,977,288 | |
| Other Administrative Action | $0 | |
| Exercise an Option | $1,347,932 | |
| Change Order | $319,510 | |
| Original award | $2,474,188 |
Show all 16
About this award
The National Institute of Allergy and Infectious Diseases awarded a definitive contract to The University of Chicago for vaccine adjuvant discovery on September 30, 2019, with a ceiling value of $9,981,721.80 under cost, no-fee pricing and ultimate completion date of April 30, 2026.
The originating solicitation, posted January 17, 2018, addresses identification of novel adjuvant candidates to augment human vaccine efficacy. The work focuses on discovering and optimizing small-molecule immune modulators that enhance innate immune activation and T-cell responses during vaccination, with specific attention to controlling excess inflammation. Formulations will be tested for compatibility with current quadrivalent vaccines and next-generation vaccine platforms, targeting improved reactogenicity, reduced dosage, and increased durability while maintaining appropriate toxicity and safety profiles. Place of performance is Chicago, IL.
Service Contract Inventory data reflects actual government-invoiced figures: FY2021 invoiced $760 thousand across 1.1 FTEs and 2,340 contractor hours at a derived rate of $324.91 per hour; FY2022 invoiced $2.4 million across 4.5 FTEs and 9,434 contractor hours at $257.91 per hour. The prime self-performed all reported hours with no subcontractors reported in FY2022. Government-paid hourly rates declined year-over-year. Valjuvant Corporation, a minority-owned small disadvantaged business, performed vaccine adjuvant formulation work as a subcontractor.
Subawards
| Subcontractor | Amount | Awarded |
|---|---|---|
| Valjuvant Corporation | $214,999 |
Quick answers
Who was awarded contract 75N93019C00041?
75N93019C00041 was awarded to The University Of Chicago by National Institute of Allergy and Infectious Diseases (National Institutes of Health) on September 30, 2019.
How much is contract 75N93019C00041 worth?
The government has obligated $9,981,722 on 75N93019C00041.
Was contract 75N93019C00041 competed?
The extent of competition for 75N93019C00041 was full and open competition. The government received 12 offers.
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