FY2025 sbir concept clearance award for topic development of therapeutic or preventative technologies for treatment or prevention of pediatric cancers and/or rare cancers.

Active Definitive Contract Awarded Last action

Contract number
75N91025C00012
Awardee
Awarding agency
Obligated
$297,621

Award facts

Contract value 100% obligated
$297,621.00 Current and potential, with all options
Completion date 57% complete
Current and potential, with all options
Set-aside
Total Small Business
Competition
Full and Open Competition after exclusion of sources · 55 offers Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
Missouri City, TX 77459, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00001 · EO 14398 -$55,000
Original award $352,621

About this award

The National Cancer Institute awarded a definitive firm fixed-price contract to Tenaci-T Therapeutics LLC for $297,621 on September 17, 2025, under a total small business set-aside. The award is an FY2025 SBIR Concept Clearance Award for development of therapeutic or preventative technologies for treatment or prevention of pediatric cancers and/or rare cancers, specifically targeting FOXM1 in glioblastoma multiforme using a novel TCR-T cell therapeutic.

The originating solicitation, posted March 28, 2024, sought proposals from small business concerns for innovative and transformative technologies in therapeutic or preventative approaches, devices, diagnostics, or digital health tools addressing pediatric and rare cancers. Proposals were required to identify an anticipated product, clinical problem, and cancer type(s) to be addressed, provide initial proof-of-concept data, and develop a business model and commercialization plan. Place of performance is Missouri City, TX. The contract period extends to September 16, 2027.

Quick answers

Who was awarded contract 75N91025C00012?

75N91025C00012 was awarded to Tenaci-T Therapeutics LLC by National Cancer Institute (National Institutes of Health) on September 17, 2025.

How much is contract 75N91025C00012 worth?

The government has obligated $297,621 on 75N91025C00012.

Was contract 75N91025C00012 competed?

The extent of competition for 75N91025C00012 was full and open competition after exclusion of sources. The government received 55 offers. It was set aside: Total Small Business.

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