Tuberculosis trials and consortium

Active Definitive Contract Awarded Last action

Contract number
75D30121C10168
Awardee
Awarding agency
Obligated
$5,623,130

Award facts

Opportunity
Contract value 57% obligated
  • $5,623,129.74 Current, with exercised options
  • $9,856,205.74 Potential, with all options
Completion date 58% complete
  • Current, with exercised options
  • Potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 22 offers Negotiated Proposal / Quote
Pricing
Cost No Fee
Place of performance
Cape Town, 7700, South Africa
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00009 · EO 14398 $0
Exercise an Option P00008 $994,681
Exercise an Option P00007 $914,196
Exercise an Option P00006 $1,040,894
Exercise an Option P00005 $860,438
Other Administrative Action P00003 $0
Supplemental Agreement for work within scope P00004 $0
Exercise an Option P00002 $850,470
Supplemental Agreement for work within scope P00001 $0
Original award $962,451

About this award

CDC Pittsburgh awarded a definitive contract to The Medical University Of South Carolina for tuberculosis trials and consortium clinical research support services on January 1, 2021, with a ceiling value of $9.86 million and performance through December 31, 2030. No set-aside was used.

The originating pre-solicitation, posted February 5, 2020, sought clinical research support to advance tuberculosis treatment, diagnosis, and prevention over a ten-year period. The government anticipated initiating up to four new studies between the base year and ninth option year, with individual phases supporting zero to two new studies while continuing enrollment, treatment, testing, and follow-up for multiple tuberculosis protocols.

Place of performance is Cape Town, South Africa. The contract operates under cost-no-fee pricing.

Service Contract Inventory reporting shows the contract invoiced $1 million in FY2024 across 41,195 contractor hours (19.8 FTEs) and $476 thousand in FY2025 across 14,235 contractor hours (6.8 FTEs), reflecting a declining trajectory in government-paid labor. Derived hourly rates were $24.98 per hour in FY2024 and $33.42 per hour in FY2025. In FY2025, three subcontractors performed 85 percent of contractor hours.

Named subcontractors include the University of Cape Town, performing pharmacokinetics-related work for TBTC Study 39 (Radiant Kids) in South Africa; Vanderbilt University Medical Center, providing site-level principal investigator leadership and clinical study support; and University of Cape Town Lung Institute, maintaining capacity for clinical study conduct including relationships with local tuberculosis programs, laboratories, and ethics oversight.

Subawards

Subcontractor Amount Awarded
University Of Cape Town TUBERCULOSIS TRIALS AND CONSORTIUM A1 5/12/2025 the scope of pharmacokinetics-related work to be undertaken by the University of Cape Town (South Africa) in… $38,359
Vanderbilt University Medical Center TUBERCULOSIS TRIALS AND CONSORTIUM A2 3/22/2024 A1 2/21/2023 Timothy R. Sterling, MD, will serve as the Site Principal Investigator will devote 5% effort in… $48,017
University Of Cape Town Lung Institute (Pty) LTD TUBERCULOSIS TRIALS AND CONSORTIUM A4 2/26/2025 A3 4/29/2024 A2 3/31/2023 A1 3/31/2022 Maintain capacity for conduct of TBTC clinical studies in the following… $3,036,194

Quick answers

Who was awarded contract 75D30121C10168?

75D30121C10168 was awarded to The Medical University Of South Carolina by CDC Pittsburgh (Centers for Disease Control and Prevention) on January 1, 2021.

How much is contract 75D30121C10168 worth?

The government has obligated $5,623,130 on 75D30121C10168. Its potential value, with all options, is $9,856,206.

Was contract 75D30121C10168 competed?

The extent of competition for 75D30121C10168 was full and open competition. The government received 22 offers.

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