The overall objective of this contract is to identify humoral correlates of protection following H3N2 M2SR vaccination, supporting the clinical development of M2SR as a strategy to induce both…

Active Definitive Contract Awarded Last action

Contract number
75A50125C00005
Awardee
Awarding agency
Obligated
$741,722

Award facts

Contract value 100% obligated
$741,722.15 Current and potential, with all options
Completion date 80% complete
Current and potential, with all options
Contracting staff
Set-aside
No set-aside
Competition
Full and Open Competition · 1 offer Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
Madison, WI 53711, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00002 $0
Other Administrative Action P00001 $0
Original award $741,722

About this award

The U.S. Department of Health and Human Services, Office of the Assistant Secretary for Preparedness and Response (ASPR), awarded a $741,722 firm-fixed-price definitive contract to Flugen Inc. on July 25, 2025, to identify humoral correlates of protection following H3N2 M2SR (monovalent mutant 2 surface reassortant) vaccination. The contract, which carries no set-aside designation and is scheduled for completion by February 28, 2027, will be performed in Madison, Wisconsin, where Flugen maintains its headquarters. The primary objective is to support clinical development of the M2SR vaccination strategy, which aims to provide both seasonal influenza immunity and pre-pandemic protection capabilities.

Flugen Inc., a biopharmaceutical company specializing in intranasal influenza vaccine technologies, brings substantial relevant experience to this research initiative. The company has previously received over $11.8 million in federal grants through the Defense Health Agency's Military Medical Research and Development program, supporting complementary research on H3N2 M2SR vaccine development, manufacturing optimization, and immunogenicity studies. This contract award represents continued federal investment in advancing innovative vaccine platforms that could benefit both military and civilian populations by enhancing pandemic preparedness and seasonal influenza protection strategies.

Description

The overall objective of this contract is to identify humoral correlates of protection following H3N2 M2SR vaccination, supporting the clinical development of M2SR as a strategy to induce both seasonal influenza immunity and pre-pandemic protection a

Quick answers

Who was awarded contract 75A50125C00005?

75A50125C00005 was awarded to Flugen Inc. by Office of the Assistant Secretary for Preparedness and Response (Department of Health and Human Services) on July 25, 2025.

How much is contract 75A50125C00005 worth?

The government has obligated $741,722 on 75A50125C00005.

Was contract 75A50125C00005 competed?

The extent of competition for 75A50125C00005 was full and open competition. The government received 1 offer.

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