Developing a next-generation vaccine that drives (a) more durable and broad anti-spike neutralizing antibodies (NABS) against variants of concern (VOCS), including those not included in the vaccine,…

Ended Definitive Contract Awarded Last action

Contract number
75A50123C00062
Awardee
Awarding agency
Obligated
$9,856,008

Award facts

Opportunity
Contract value 2% obligated
  • $9,856,008.00 Current, with exercised options
  • $433,190,532.00 Potential, with all options
Completion date 100% complete
  • Current, with exercised options
  • Potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 1 offer Negotiated Proposal / Quote
Pricing
Cost Plus Fixed Fee
Place of performance
Boston, MA 02215, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Other Administrative Action P00004 · EOI::presidential cost savings initiative (february 26, 2025)::EOI modification to transmit fpds data $0
Other Administrative Action P00003 $0
Other Administrative Action P00002 $0
Supplemental Agreement for work within scope P00001 $0
Original award $9,856,008

About this award

Gritstone Bio, Inc. was awarded a $433.2 million cost-plus-fixed-fee definitive contract by the Office of the Assistant Secretary for Preparedness and Response (ASPR) to develop a next-generation vaccine designed to elicit durable and broad anti-spike neutralizing antibodies against variants of concern, including those not represented in the vaccine formulation, while simultaneously generating T cells reactive against conserved targets. The contract, awarded on September 25, 2023, with performance based in Boston, Massachusetts, carries an ultimate completion date of July 2, 2026, and includes no set-aside designation.

This award originated from a Broad Agency Announcement issued by the Biomedical Advanced Research and Development Authority (BARDA) in October 2017, which sought proposals for advanced research and development of medical countermeasures against chemical, biological, radiological, nuclear, and pandemic influenza threats. The solicitation encompassed multiple focus areas including vaccines, therapeutics, diagnostics, and related technologies to advance candidates toward FDA approval or licensure. Gritstone Bio's vaccine development effort aligns with BARDA's core mission of accelerating the development of medical countermeasures to address emerging pandemic and biological threats, leveraging ASPR's resources to support the advancement of critical public health capabilities.

Description

Developing a next-generation vaccine that drives (a) more durable and broad anti-spike neutralizing antibodies (NABS) against variants of concern (VOCS), including those not included in the vaccine, and (B) T cells reactive against conserved targets

Quick answers

Who was awarded contract 75A50123C00062?

75A50123C00062 was awarded to Gritstone Bio, Inc. by Office of the Assistant Secretary for Preparedness and Response (Department of Health and Human Services) on September 25, 2023.

How much is contract 75A50123C00062 worth?

The government has obligated $9,856,008 on 75A50123C00062. Its potential value, with all options, is $433,190,532.

Was contract 75A50123C00062 competed?

The extent of competition for 75A50123C00062 was full and open competition. The government received 1 offer.

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