Venatorx pharmaceuticals: new antibiotics to treat drug-resistant gram-negative bacteria including public health pathogens.

Active Definitive Contract Awarded Last action

Contract number
75A50123C00050
Awardee
Awarding agency
Obligated
$45,192,122

Award facts

Opportunity
Contract value 24% obligated
  • $45,192,122.00 Current, with exercised options
  • $191,938,367.00 Potential, with all options
Completion date 50% complete
  • Current, with exercised options
  • Potential, with all options
Contracting staff
Set-aside
No set-aside
Competition
Full and Open Competition · 1 offer Negotiated Proposal / Quote
Pricing
Cost Sharing
Place of performance
Malvern, PA 19355, USA

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Funding Only Action P00009 · The purpose of this modification is to: $5,429,906
Exercise an Option P00008 · The purpose of this modification is to exercise CLIN0002/option 1, update the period of performance for CLIN0001/base through december 31, 2027, and section… $13,312,363
Exercise an Option P00007 · The purpose of this modification is to exercise CLIN0005/option 4, update articles g.3 key personnel, g.4.g contract financial report, g.8 post award evaluation… $6,128,136
Novation Agreement P00006 · The purpose of this modification is to finalize the novation agreement via this modification the united states government recognizes that all contractual… $0
Other Administrative Action P00005 · The purpose of this no-cost modification is to update article g.7 indirect cost rates based on documentation from NIH dated april 23, 2025, and article i.1… $0
Other Administrative Action P00004 · The purpose of this modification is to update articles i.1 federal acquisition regulation (far) (48 CFR chapter 1) clauses, 52.204-14 services contract… $0
Other Administrative Action P00003 · The purpose of this modification is to update article g.1 contracting officer, article g.3 key personnel, and update attachment #1 - statement of work dated… $0
Other Administrative Action P00002 · The purpose of this modification is to update article g.7 indirect cost rate $0
Other Administrative Action P00001 · No cost modification to update section g.3 key peronnel $0
Original award $20,321,717

About this award

The Office of the Assistant Secretary for Preparedness and Response awarded a definitive cost-sharing contract to Basilea Pharmaceutica International Ltd for development of new antibiotics to treat drug-resistant gram-negative bacteria on September 15, 2023, with a ceiling value of $191.9 million.

This modification extends the period of performance for the base effort (CLIN0001) through December 31, 2029, provides supplemental funding for CLIN0001, and adds activities under CLIN0002 at no additional cost to the government. The contract targets development of a new class of antibiotics addressing lipopolysaccharide transport and inhibitors of the DXR enzyme, with focus on high-priority pathogens including carbapenem-resistant Enterobacteriaceae, Acinetobacter baumannii, and multidrug-resistant Pseudomonas aeruginosa. Place of performance is Malvern, PA. The originating solicitation issued from the Biomedical Advanced Research and Development Authority as a broad agency announcement seeking advanced research and development of medical countermeasures against chemical, biological, radiological, nuclear, and pandemic influenza threats, with relevant NAICS codes 541711 and 541712.

Quick answers

Who was awarded contract 75A50123C00050?

75A50123C00050 was awarded to Basilea Pharmaceutica International Ltd, Allschwil by Office of the Assistant Secretary for Preparedness and Response (Department of Health and Human Services) on September 15, 2023.

How much is contract 75A50123C00050 worth?

The government has obligated $45,192,122 on 75A50123C00050. Its potential value, with all options, is $191,938,367.

Was contract 75A50123C00050 competed?

The extent of competition for 75A50123C00050 was full and open competition. The government received 1 offer.

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