Treatment for use in a mass casualty event where thrombocytopenia or platelet loss is a major concern.

Active Definitive Contract Awarded Last action

Contract number
75A50122C00065
Awardee
Awarding agency
Obligated
$839,875,190

Award facts

Opportunity
Contract value 85% obligated
  • $839,875,189.59 Current, with exercised options
  • $982,693,989.59 Potential, with all options
Completion date 41% complete
Current and potential, with all options
Set-aside
No set-aside
Competition
Full and Open Competition · 1 offer Negotiated Proposal / Quote
Pricing
Firm Fixed Price
Place of performance
Thousand Oaks, CA 91320, USA
Legislative mandates

Award details come from SAM.gov/FPDS.

Transactions

Action Obligated Date
Supplemental Agreement for work within scope P00008 · EO14398 for far 52.222-90, updated hhsar and exercise option period 4A for $65,698,998.00 $65,996,183
Supplemental Agreement for work within scope P00007 · Exercise option period 4 and modify the number of doses. Change the period of performance to march 4, 2026 through september 29, 2032. The total contract funded… $59,988,838
Exercise an Option P00006 · Exercise option period 3 clins 0010, 0011, and 0012. $89,975,028
Other Administrative Action P00005 · Revise option period 2 clins 0007 - 0009 period of performance. $0
Funding Only Action P00004 · Exercise option period 2 clins 0007 - 0009 for the procurement of 62,896 units of nplate pharmaceutical products. $128,996,651
Other Administrative Action P00003 · No cost modification to revise section b.2.2, clin table description column for CLIN0005. $0
Exercise an Option P00002 · Amgen - exercise optional clins 0004, 0005, and 0006. Add far clause 52.204-27. $204,858,569
Other Administrative Action P00001 · Amgen - unilateral modification to revise the contracting officer. $0
Original award $290,059,920

About this award

The Office of the Assistant Secretary for Preparedness and Response awarded a definitive contract to Amgen USA Inc. for treatment of thrombocytopenia in mass casualty events resulting from acute radiation syndrome on September 30, 2022, with a ceiling value of $982.69 million and ultimate completion on September 29, 2032.

The contract is firm fixed price with no set-aside. The originating solicitation, posted June 15, 2022, sought an FDA-approved thrombopoietin receptor agonist using Project BioShield funds to treat thrombocytopenia arising from hematopoietic acute radiation syndrome. The therapeutic must increase survival in adults and pediatric patients exposed to myelosuppressive radiation doses and be effective when administered 24 or more hours post-radiation exposure. The procured therapeutic will be delivered to the Strategic National Stockpile and maintained as vendor managed inventory.

Place of performance is Thousand Oaks, CA. The contract exercise includes option period 4A valued at $65.70 million.

In fiscal year 2024, Amgen USA Inc. invoiced $204.8 million across 0.4 FTEs and 729 contractor hours, with a derived government-paid hourly rate of $280,888.83. The awardee self-performed all reported hours without subcontractors.

Quick answers

Who was awarded contract 75A50122C00065?

75A50122C00065 was awarded to Amgen USA Inc. by Office of the Assistant Secretary for Preparedness and Response (Department of Health and Human Services) on September 30, 2022.

How much is contract 75A50122C00065 worth?

The government has obligated $839,875,190 on 75A50122C00065. Its potential value, with all options, is $982,693,990.

Was contract 75A50122C00065 competed?

The extent of competition for 75A50122C00065 was full and open competition. The government received 1 offer.

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