Center for Surveillance

The Centers for Disease Control and Prevention (CDC), a sub-agency of the Department of Health and Human Services, administers federal grant funding for public health surveillance, disease prevention, emergency preparedness, and health-protection programs at the state and local level. The CDC has obligated $28.17 billion in federal grant dollars across 364 awards since 2010, funding state health departments, research institutions, and public health networks.

Recent grant activity shows significant volatility. The CDC closed 17 awards in 2021, surged to 125 awards in 2022, then dropped to 5 awards in 2023 and 10 in 2024, with 1 award recorded in 2026. The most recent grant award closed on April 3, 2026. Across the portfolio, 202 distinct recipients have received funding, indicating a fragmented recipient base — the top five recipients by award count account for 9 percent of recent awards, and the top five by federal dollars account for 12 percent of obligated federal funds.

State health departments dominate the recipient landscape. The Florida Department of Health leads both by award count and by federal dollars, holding 4 awards totaling $1.18 billion obligated. The National Network of Public Health Institutes Inc. ranks second by federal dollars with 2 awards and $849.1 million obligated. The California Department of Public Health, Alabama Department of Health, and Tennessee Department of Health each hold 2 awards with federal obligations ranging from $395 million to $440.7 million. The South Carolina Department of Public Health and Utah Department of Health and Human Services also appear among top recipients, each with 2–3 awards.

The CDC's grant portfolio is heavily weighted toward Cooperative Agreements, which account for 259 of 364 awards (71 percent), with the remaining 29 percent structured as Project Grants. Cooperative Agreements indicate active federal involvement in performance alongside recipients, whereas Project Grants support recipient-directed work with less day-to-day federal oversight.

No recent federal grant opportunities are recorded in the source data. Business development professionals should monitor the CDC's funding opportunity portal and subscribe to state health department grant announcements, as the award activity pattern and state-centric distribution suggest future solicitations will target public health emergency response, surveillance infrastructure, and capacity-building at the state and local level.