Louisiana State University Health Sciences Center New Orleans

Louisiana State University Health Sciences Center New Orleans, a state government academic medical center based in New Orleans, delivers biomedical research and specialized clinical services to the federal government as a prime recipient on federal grants and a prime contractor on clinical service delivery contracts, competing in full-and-open procurements without set-aside designation. The institution is a child entity of Louisiana State University.

The center's federal footprint centers on biomedical and health services research. Its grant portfolio spans the National Institutes of Health (NIH)—particularly the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), and National Heart, Lung, and Blood Institute (NHLBI)—as well as the National Science Foundation, Centers for Disease Control and Prevention, Defense Health Agency, and the Department of Veterans Affairs. Representative research grants include a $1.27 million NIAAA award for geroprotective precision medicine strategies targeting premature aging in people with HIV who use alcohol (CFDA 93.273, FY2026–2030); a $567.832 thousand NIAAA project grant for reducing alcohol drinking with a nonmuscle myosin II small-molecule inhibitor targeting alcohol use disorder (CFDA 93.273, FY2026–2031); a $1.008719 million National Heart, Lung, and Blood Institute project grant for screening and validation of microRNA targets for neurogenic hypertension (CFDA 93.837, FY2026–2033); and a $7.49 million NSF EPSCOR CREST Phase 1 project grant establishing a Center for Adaptive Nanomotor Development (CFDA 47.076, FY2025–2030). On the contract side, the institution holds a $464.525 thousand single-award indefinite delivery contract from the Department of Veterans Affairs Veterans Integrated Service Network 16 for offsite teleradiology services through September 2026, and multiple related contracts for anatomical autopsy services to the VA Medical Center in New Orleans (total ceiling of $36 thousand through March 2026).

Recent grant awards cluster heavily in alcohol use disorder research, cancer prevention and control, cardiovascular disease, and infectious diseases. The institution acts as prime recipient on direct-to-institution awards and as sub-recipient under larger prime grants—recent examples include sub-award roles under University of Hawaii, University of California Los Angeles, Johns Hopkins University, Lurie Children's Hospital, University of New Mexico, and Pennington Biomedical Research Center. The institution also serves as a sub-recipient partner on the Louisiana Clinical & Translational Science Center (LA CaTS) with Pennington Biomedical and on the Stanley S. Scott Cancer Center's collaborative networks in sub-Saharan Africa (Zambia, Tanzania).

On contracts, the center performs as a clinical services provider and research site. SCI-reportable federal service contract invoicing totaled $6.6 million across FY2022–FY2024, with FY2024 invoicing of $2.3 million across 15.4 FTEs delivered on four prime contracts and one sub-contract. Government-paid rates on these service contracts ranged from a 10th percentile of $53.17/hr to a 90th percentile of $191.06/hr, with a median around $78.32/hr. The institution delivers primarily self-performed labor; across SCI-reportable prime contracts, subcontractors accounted for an average 7% of total contractor hours, with nine named subs engaged over the reporting period. Recent contract sub-awards include clinical trial implementation work under Axle Informatics, LLC (development and management of Phase 2 clinical trials evaluating vaccines against Neisseria gonorrhoeae infection; awards August 2024 and October 2024) and data collection activities under GE Medical Systems Information Technologies for an AI-enabled ultrasound study funded by BARDA (award May 2025).

The center's customer concentration is heavily weighted toward HHS/NIH, which dominates both award count and dollar value; the top five customer agencies account for 49% of recent awards. NCI represents the largest single funding source by dollar potential value at $927.8 million across 57 awards. The recompete cliff shows 57 awards with ultimate completion dates in the next twenty-four months, carrying $18.1 million in combined potential value. Work is performed in New Orleans, Louisiana, with some collaborative and training components distributed across Louisiana (Baton Rouge, Lake Charles) and nationally through sub-recipient and consortium partnerships. The institution maintains active research infrastructure supporting preclinical and clinical research, diagnostic services (pathology, radiology), and public health programs focused on cancer prevention, health disparities reduction, and training of the health professions workforce.