In Vitro Pharmacology Assays (UW-MAD) [18-5827-R1]

The University of Wisconsin-Madison's Purchasing Services Department is soliciting bids for specialized In Vitro Pharmacology Assays through Request for Bid (RFB) 18-5827-R1, targeting vendors capable of providing comprehensive laboratory testing services for drug development research. The procurement seeks services including aqueous solubility assays, lipophilicity testing, plasma and microsome stability assays, permeability testing, plasma protein binding assays, cytotoxicity assessments, cytochrome P450 inhibition assays, chemical stability analysis, and method development for small molecule compounds. Bidders must have been in business providing these services for at least two years and submit three client references from comparable institutions. The RFB was issued on October 9, 2017, with written questions due by October 16, 2017, and sealed bids due by October 26, 2017, at 2:00 p.m. CDT. The University will evaluate bids based on lowest overall cost and reserves the right to conduct oral presentations, product demonstrations, and site visits. Pricing must be submitted as firm net unit prices for each specified assay on an Excel spreadsheet, with non-listed related items available at a single percentage discount from manufacturer catalogs.

The contract does not specify set-aside designations for disadvantaged enterprises, but it includes provisions for potential multi-campus utilization, allowing extension to other UW System campuses, Wisconsin state agencies, and municipalities. The initial contract term is one year from execution, with automatic renewal options for two additional one-year periods, contingent upon 90-day written notice from either party. The estimated annual volume is approximately 100 compounds, with studies ranging from 1 to 20 compounds per study and an estimated annual cost exceeding $50,000. Contractors are required to maintain $1,000,000 minimum liability insurance and preserve records for five years post-payment. The University will make awards judged to be in the best institutional interest and may issue multiple contracts. Pricing must remain firm throughout the initial contract term, with any subsequent price increases requiring 30 days' written notice and cost justification documentation. No minimum order quantities are permitted, providing flexibility for the University's research needs.