Undiagnosed Diseases Network (UDN) Clinical Networks of Diagnostic Excellence
Forecasted Federal grant Posted
- Opportunity number
- PAR-27-137
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- County Governments
- State Governments
- Tribal Organizations (Not Federally Recognized)
- 501(c)(3) Nonprofits
- Independent School Districts
- Other
- Tribal Governments (Federally Recognized)
- Special District Governments
- Non-501(c)(3) Nonprofits
- Small Businesses
- Higher Education Inst. (Private)
- City/Township Governments
- Public or Indian Housing Auth.
- For Profit Organizations
- Higher Education Inst. (Public)
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Neurological Disorders and Stroke (NINDS) is forecasting support for multiple Undiagnosed Diseases Network (UDN) Clinical Networks of Diagnostic Excellence through cooperative agreements; applications are not currently being solicited. This represents a shift from prior UDN phases toward geographically distributed regional clinical networks rather than single-site centers, requiring applicants to establish partnerships with academic medical centers, hospitals, clinics, federally qualified health centers, and community-based clinical partners.
Eligible applicants include county and state governments, federally recognized and non-federally recognized tribal organizations, 501(c)(3) and non-501(c)(3) nonprofits, independent school districts, special district governments, small businesses, for-profit organizations, public or Indian housing authorities, faith-based or community-based organizations, regional organizations, eligible federal agencies, higher education institutions (public and private), city and township governments, U.S. territories or possessions, and Indian/Native American tribal governments other than federally recognized.
Clinical NODEs will recruit and enroll participants with highly challenging, difficult-to-diagnose conditions; conduct multidisciplinary, participant-centered evaluations; coordinate with partner sites; develop and test innovative diagnostic tools for genomic and non-genomic conditions; support systematic re-evaluation of unsolved cases; and conduct research to optimize participant access. All NODEs must participate in network governance, provide training to support consistent UDN processes, incorporate participant and community input through mechanisms such as Community Advisory Boards, and monitor site performance.
Awards fall under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders). The program evaluates proposals on scientific merit, technical adequacy, investigator competency, facility adequacy, budget necessity, and relevance to program objectives.
Forecast synopsis
NINDS intends to support multiple clinical Networks of Diagnostic Excellence (NODEs) as part of the next phase of the Undiagnosed Diseases Network (UDN). Unlike prior phases, clinical NODEs are expected to function as geographically distributed regional clinical networks rather than single-site centers. Each clinical NODE would establish and lead a regional network built on existing partnerships with academic medical centers, hospitals, clinics, federally qualified health centers, and other community-based clinical partners to broaden access to specialized diagnostic expertise and extend the reach of the UDN.
Clinical NODEs are expected to provide a coordinated, multidisciplinary and participant-centered evaluation of individuals with highly challenging, difficult-to-diagnose conditions. In collaboration with the Network, clinical NODEs will recruit and enroll participants, conduct medical record reviews, make enrollment determinations, communicate review outcomes and recommendations to participants and referring providers, and coordinate the clinical evaluation with local partner sites and referring providers, as appropriate.
In addition, clinical NODEs will participate in network collaborations to develop and test innovative, new diagnostic tools and strategies for both genomic and non-genomic conditions, support systematic re-evaluation of unsolved UDN cases, and conduct research to optimize participant access and experience. Clinical NODEs are also expected to participate in network governance and infrastructure; provide training to support consistent implementation of UDN processes and standards; incorporate participant and community input into workflows and engagement strategies, such as through a Community Advisory Board or comparable mechanisms; and monitor site performance.
Applications are not being solicited at this time. This Forecast is being published to provide potential applicants time to plan, establish collaborations, formalize regional partnerships, and prepare responsive projects.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.
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