Transformative Non-Invasive/Minimally Invasive Technologies for Imaging the Olfactory System Across Scales (R01 CT Optional)
Open Posted
- Opportunity number
- RFA-DC-27-003
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Up to $500,000
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- County Governments
- Other
- Higher Education Inst. (Public)
- Independent School Districts
- Special District Governments
- Non-501(c)(3) Nonprofits
- Small Businesses
- City/Township Governments
- Tribal Governments (Federally Recognized)
- Tribal Organizations (Not Federally Recognized)
- 501(c)(3) Nonprofits
- Public or Indian Housing Auth.
- For Profit Organizations
- Higher Education Inst. (Private)
- State Governments
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute on Deafness and Other Communication Disorders (NIDCD), partnering with the National Institute of Biomedical Imaging and Bioengineering (NIBIB), is forecasting a Notice of Funding Opportunity to solicit R01 research grant applications for transformative non-invasive and minimally invasive imaging technologies targeting the human olfactory system, with an application due date of August 21, 2028.
Eligible applicants include county governments, higher education institutions (public and private), state governments, city and township governments, tribal governments (federally recognized) and tribal organizations (not federally recognized), special district governments, independent school districts, 501(c)(3) and non-501(c)(3) nonprofits, small businesses, for-profit organizations, and public or Indian housing authorities. Non-domestic entities and foreign components of U.S. organizations are not eligible to apply.
Applications must leverage advanced non-invasive or minimally invasive imaging technologies—including cell-specific biomarkers, fluorescence imaging, specialized endoscopes, optical and acoustic imaging, molecular imaging, and hemodynamic or diffusion imaging—to visualize peripheral olfactory targets (olfactory and non-olfactory epithelium) and central olfactory targets (olfactory bulb) at previously unattainable resolution levels. Projects must engage multidisciplinary teams combining expertise in olfaction, biomedical imaging, biochemistry, bioengineering, and biophysics.
The opportunity falls under two federal grant programs: Research Related to Deafness and Communication Disorders (CFDA 93.173) and Discovery and Applied Research for Technological Innovations to Improve Human Health (CFDA 93.286). Funding supports salaries, equipment, supplies, travel, and indirect costs. Applications undergo NIH peer review by technical panels and the National Deafness and Other Communication Disorders Advisory Council, with typical review timelines of 6 to 9 months from submission to funding decision. Award notices have not yet been published; this notice provides time for applicants to develop collaborations before the formal NOFO appears.
Synopsis
The National Institute on Deafness and Other Communication Disorders (NIDCD), with the National Institute of Biomedical Imaging and Bioengineering (NIBIB) aims to support the development and/or adaptation of transformative in vivo high-resolution/high specificity imaging of the human olfactory system. Currently, there are limited non-invasive/minimally invasive technologies available for imaging the living human peripheral and central olfactory system with high spatial and temporal resolution. Imaging the olfactory system in the laboratory and in the clinic is essential to understanding underlying biological mechanisms as well as the etiology of an olfactory disorder. Such imaging has proven challenging due to the olfactory system"s unique anatomical and functional characteristics such as restricted accessibility, multiple cell types, and low signal resolution. Addressing these challenges requires multimodal approaches including leveraging existing advanced tools and technologies and developing new tools tailored for the olfactory system. Recent advances in minimally invasive and non-invasive imaging technologies, such as cell specific biomarkers, fluorescence imaging, specialized endoscopes, optical and acoustic imaging, molecular imaging, and hemodynamic and diffusion imaging have the potential to transform our ability to image and investigate the peripheral and central olfactory system in the living human with superior temporal and spatial resolution and eventually improve diagnostic accuracy of olfactory disorders. Applications must leverage advanced non-invasive/minimally invasive imaging technologies to visualize peripheral (e.g., olfactory- and non-olfactory epithelium) and central olfactory (e.g., olfactory bulb) targets at a level previously unattainable. In addition, projects should engage multidisciplinary teams combining expertise in olfaction, biomedical imaging, biochemistry, bioengineering, and biophysics, as appropriate.
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Files
| File | Type | Posted |
|---|---|---|
| PKG00292863.pdf | ||
| RFA-DC-27-003-Full-Announcement.html | HTML file |
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