The Role of the Innate Immune System in the Pathogenesis of Type 1 Diabetes
Forecasted Federal grant Posted
- Opportunity number
- RFA-AI-28-029
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Public or Indian Housing Auth.
- Tribal Organizations (Not Federally Recognized)
- County Governments
- City/Township Governments
- Small Businesses
- Independent School Districts
- State Governments
- Higher Education Inst. (Private)
- Non-501(c)(3) Nonprofits
- Higher Education Inst. (Public)
- 501(c)(3) Nonprofits
- Tribal Governments (Federally Recognized)
- Other
- For Profit Organizations
- Special District Governments
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Allergy and Infectious Diseases (NIAID) seeks applicants for cooperative agreement funding to support research on the role of the innate immune system in Type 1 diabetes pathogenesis, utilizing Special Statutory Funding Program for Type 1 Diabetes Research funds. This is a forecast opportunity with no hard application deadline specified in the source.
Eligible applicants include public and private nonprofit institutions, state and local governments, small businesses, Indian tribes (federally and nonfederally recognized), faith-based and community-based organizations, foreign institutions, U.S. territorial entities, and for-profit organizations. The program targets multidisciplinary research teams with expertise in innate immunity and beta-cell biology to elucidate how innate immune components interact with pancreatic tissues and beta cells.
Research emphasis focuses on identifying genetic and environmental causes of Type 1 diabetes as mandated by the congressionally established Special Diabetes Program. Applicants are expected to employ new approach methodologies (NAMs) to define the timing and impact of environmental perturbations activating innate immune pathways. Successful projects should enable earlier identification of individuals at elevated risk for Type 1 diabetes beyond genetic susceptibility and establish groundwork for prevention and therapeutic strategies.
Applications will be evaluated on scientific merit and general significance of proposed objectives, technical adequacy of experimental design and approach, investigator competency, adequacy of facilities and resources, budget necessity relative to project scope, and relevance to announced program objectives. Standard peer review by an appropriate initial review group and National Advisory Allergy and Infectious Diseases Council will occur. Award details including funding level, number of awards, and period of performance are not specified in this forecast announcement.
Funding derives from CFDA 93.855 (Allergy and Infectious Diseases Research) under authorities 42 USC 241 and 284 and 42 CFR Part 52.
Forecast synopsis
The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by utilizing Special Statutory Funding Program for Type 1 Diabetes Research funds to support studies focused on the involvement of the innate immune system in the initiation of Type 1 diabetes (T1D). This initiative directly aligns with the first goal of the congressionally mandated Special Diabetes Program, which is to identify the genetic and environmental causes of T1D. By engaging multidisciplinary teams with expertise in innate immunity and beta-cell biology, the program aims to elucidate how innate immune components interact with pancreatic tissues and beta cells. The program will leverage the use of new approach methodologies (NAMs) to precisely define the timing and impact of environmental perturbations that activate innate immune pathways. Ultimately, these studies may enable earlier identification of individuals at elevated risk for T1D (beyond genetic susceptibility) and lay the groundwork for future prevention and therapeutic strategies. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
On GovTribe
Work this opportunity
- Track it in your pipeline
- Find teaming partners
- Similar grant opportunities
- Ask GovTribe AI about this opportunity