The NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genomic Research Centers
Forecasted Federal grant Posted
- Opportunity number
- RFA-DK-27-116
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Other
- For Profit Organizations
- County Governments
- Independent School Districts
- State Governments
- Tribal Organizations (Not Federally Recognized)
- Special District Governments
- 501(c)(3) Nonprofits
- Higher Education Inst. (Public)
- Public or Indian Housing Auth.
- Higher Education Inst. (Private)
- Small Businesses
- City/Township Governments
- Tribal Governments (Federally Recognized)
- Points of contact
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- Ludmila Pawlikowska ludmila.pawlikowska@nih.gov (301) 480-9372
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Diabetes and Digestive Diseases and Nutrition (NIDDK) seeks applicants for the Inflammatory Bowel Disease Genetics Consortium (IBDGC) Genomic Research Centers cooperative agreement, a forecast opportunity with no application deadline specified in the source.
The IBDGC will establish up to 7 Genomic Research Centers serving as sites for participant enrollment, molecular analysis of biospecimens, and bioinformatics and computational analyses. The consortium aims to characterize interactions of genetic, clinical, and environmental factors in IBD development and progression, and to develop predictors of disease outcomes including remission, recurrence, and therapy response, with the goal of advancing precision medicine for IBD patients.
Eligible applicants include higher education institutions (public and private), 501(c)(3) nonprofits, state and local governments, tribal governments (federally and non-federally recognized), small businesses, for-profit organizations, and other eligible entities including faith-based organizations, regional organizations, U.S. territories, and non-domestic entities. The source does not specify cost share requirements, award ceilings, award floors, expected number of awards, period of performance, or place of performance.
The program funds basic and clinical biomedical research improving understanding of diabetes, digestive, and kidney diseases under CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research). Scientific merit review assesses the significance of proposed objectives, technical adequacy of design, investigator competency, facility adequacy, budget necessity, and relevance to program objectives. The IBDGC leverages existing patient cohorts and biospecimens to advance understanding of IBD heterogeneity and develop outcome prediction tools.
Forecast synopsis
The National Institute of Diabetes and Digestive Diseases and Nutrition (NIDDK) seeks to advance its mission by continuing the NIDDK Inflammatory Bowel Disease Genetics Consortium (IBDGC). The IBDGC has led collaborative efforts resulting in the identification of >300 genetic risk loci for different IBD subtypes across patient populations and characterization of underlying biological mechanisms. Despite advances in biological understanding and the development of a range of biologic therapies, IBD remains a chronic, severe and heterogenous disease with no cure requiring multiple interventions over the life course. Diagnostic biomarkers and accurate predictors of critical outcomes including disease remission, recurrence, and response to specific therapies are lacking. The IBDGC will leverage patient cohorts, biospecimens and advances in data science to characterize the interactions of genetic, clinical and environmental factors in disease development and progression, and to develop new predictors of disease outcomes, with the goal of improving medical management and advancing precision medicine for IBD patients. The IBDGC may include up to 7 Genomic Research Centers with varying research emphases, which will serve as sites for participant enrollment, molecular analysis of biospecimens and bioinformatics and computational analyses.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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