Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE, RP1 Clinical Trial Not Allowed)
Past Federal grant forecast Posted
- Opportunity number
- PAR-26-129
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- State Governments
- Public or Indian Housing Auth.
- Tribal Organizations (Not Federally Recognized)
- For Profit Organizations
- City/Township Governments
- Other
- Higher Education Inst. (Public)
- Special District Governments
- Independent School Districts
- Higher Education Inst. (Private)
- County Governments
- Small Businesses
- Tribal Governments (Federally Recognized)
- Non-501(c)(3) Nonprofits
- 501(c)(3) Nonprofits
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Cancer Institute is soliciting applications for the Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) program to support preclinical research investigating biological effects of radiation emitted by radionuclides used in radiopharmaceutical therapy, with no hard deadline specified in this forecast notice.
Eligible applicants include state and local governments, tribal organizations (federally and non-federally recognized), for-profit organizations, higher education institutions (public and private), small businesses, 501(c)(3) and non-501(c)(3) nonprofits, independent school districts, special districts, public or Indian housing authorities, Indian/Native American tribal governments, eligible federal agencies, U.S. territories or possessions, faith-based or community-based organizations, regional organizations, and non-domestic entities.
The program operates under two project tracks: exploratory/developmental research projects with a project period of up to 2 years, or research projects with a project period of 4 to 5 years. Applicants may select either track when submitting.
STRIPE consolidates prior exploratory and research project funding mechanisms to streamline applications and sustain momentum in radiopharmaceutical therapy research. Funded projects must integrate cancer biology, radiation biology, radiochemistry, imaging, dosimetry, and preclinical modeling to generate mechanistic insights supporting development of new targeting strategies, optimized treatment regimens, and combination approaches for radiopharmaceutical therapy. The initiative aims to broaden the scientific base, lower barriers to entry for cancer biology investigators, and accelerate reproducible, mechanistically informed data generation.
The opportunity is assigned to two parent grant programs: Cancer Detection and Diagnosis Research (CFDA 93.394) and Cancer Treatment Research (CFDA 93.395). Scientific merit, program relevance, and program balance consistent with NCI and NIH priorities drive funding decisions. No cost share requirement, award ceiling, or award floor is specified in the source material.
Forecast synopsis
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to support research projects that employ state-of-the-art cancer biology approaches and preclinical model systems to investigate the biological effects of radiation emitted by radionuclides used in radiopharmaceutical therapy (RPT). The focus of this initiative is to advance mechanistic understanding of how different forms of radionuclide-emitted radiation affect normal tissues, tumor cells, and the tumor microenvironment, and how these effects can be leveraged to improve therapeutic outcomes. This NOFO will support the Systematic Testing of Radionuclides in Preclinical Experiments (STRIPE) program. The overarching goal of STRIPE is to stimulate multidisciplinary research that integrates cancer biology, radiation biology, radiochemistry, imaging, dosimetry, and preclinical modeling. Funded projects are expected to generate fundamental biological insights that can serve as the foundation for the development of new targeting strategies, optimized treatment regimens, and innovative combination approaches for RPT, ultimately leading to more effective and precise anticancer therapies.
This NOFO consolidates prior exploratory/developmental and research project funding mechanisms to streamline the application process and sustain momentum in this critical research area. The applicants have the option of submitting either for exploratory/developmental research projects with a project period of up to 2 years or for research projects with a project period of 4 to 5 years. Collectively, the STRIPE program is intended to broaden the scientific base of RPT research, lower barriers to entry for cancer biology investigators, and accelerate the generation of reproducible, mechanistically informed data that will enable more effective and personalized use of radiopharmaceutical therapies in cancer care.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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