The Centers for Medicare & Medicaid Services, (CMS) Center for Medicare and Medicaid Innovation (Innovation Center) is interested in testing new care and payment models that have the potential to improve perinatal outcomes for women enrolled in Medicaid who are at high-risk for adverse pregnancy outcomes. This initiative is a partnership between the Innovation Center and the Center for Medicaid and CHIP Services (CMCS) and part of a larger HHS effort to improve maternal and infant health outcomes. In this four-year initiative the Innovation Center will offer a funding opportunity to eligible applicants to test the impact of providing enhanced prenatal care interventions for women with Medicaid coverage who are at high risk for having a preterm birth. The initiative will test 3 distinct approaches to providing enhanced prenatal care delivery. Each approach provides a set of specific and comprehensive interventions to improve current, traditional prenatal care delivery and address additional clinical, behavioral, and psychosocial factors that may be present during pregnancy and contribute to preterm-related poor birth outcomes.