Single Source for Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium - Data Coordinating Center (DCC)
Past Federal grant forecast Posted
- Opportunity number
- RFA-DK-27-138
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- County Governments
- 501(c)(3) Nonprofits
- Non-501(c)(3) Nonprofits
- Other
- Higher Education Inst. (Public)
- Small Businesses
- Public or Indian Housing Auth.
- Tribal Organizations (Not Federally Recognized)
- State Governments
- For Profit Organizations
- Higher Education Inst. (Private)
- Tribal Governments (Federally Recognized)
- Points of contact
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- Tracy Rankin niddk_kuh@nih.gov (301) 594-6417
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health is soliciting a renewal application for a Data Coordinating Center supporting the Consortium to Study Chronic Kidney Disease of Uncertain Etiology (CKDu) in Agricultural Communities (CURE) through a cooperative agreement; this is a forecast opportunity with no posted application deadline. Eligible applicants include county governments, 501(c)(3) nonprofits, non-501(c)(3) nonprofits, higher education institutions (public and private), small businesses, tribal organizations (federally and non-federally recognized), state governments, for-profit organizations, public or Indian housing authorities, other eligible agencies of the federal government, U.S. territories or possessions, faith-based or community-based organizations, regional organizations, and non-domestic entities.
The Data Coordinating Center will provide data management and analysis and overall project management for a multi-site consortium funded since 2021 by NIDDK, NIEHS, and FIC. The consortium includes Field Epidemiology Sites and a Renal and Environmental Science Core. CKDu causes kidney failure in rural areas of low and middle income countries; this research addresses tubulointerstitial renal disease with implications for U.S. kidney health. The DCC will enable discovery science to identify etiologies of CKDu, characterize exposures initiating and affecting disease progression, identify potential therapeutic targets, and support opportunities for public health interventions. The consortium will also serve as a resource for ancillary studies.
All applications will undergo peer review and receive funding only if meritorious. This opportunity is assigned to CFDA 93.847 (Diabetes, Digestive, and Kidney Diseases Extramural Research).
Forecast synopsis
The purpose of this funding opportunity is to advance the NIH mission by supporting the continuation of the Consortium to Study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE).
Chronic Kidney Disease of Uncertain Etiology (CKDu) causes kidney failure in rural areas of many Low and Middle Income Countries, resulting in a large death toll among the young working age population. Environmental factors are suspected to be causative, but family and geographic clustering add consideration of unrecognized genetic susceptibility. The risk factors identified in other countries are encountered by U.S. patients, so this research will offer valuable insights into the development and progression of tubulointerstitial renal diseases, with broad implications for understanding kidney health and disease in the U.S.
NIDDK, NIEHS, and FIC have jointly funded a consortium that includes Field Epidemiology Sites, a Renal and Environmental Science Core, and a Data Coordinating Center to find causes and potential interventions for CKDu since 2021. This NOFO requests a renewal application for the Data Coordinating Center that will provide data management and analysis, as well as overall project management for the Consortium. Consortium members will continue to collaborate to maximize scientific opportunities and enable discovery science to understand the etiologies of CKDu, the exposures that initiate and affect progression of tubulointerstitial kidney disease, potential therapeutic targets, and future opportunities for public health interventions. The CURE Consortium will serve as a resource for ancillary studies.
This is a forecast for a single source Notice of Funding Opportunity (NOFO) that will invite application(s) from eligible organizations to apply. Application(s) will be peer-reviewed and only funded if meritorious.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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