Single Source: Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Data Processing, Analysis, and Coordination Center (DPACC) (U24 Clinical Trial Not Allowed)

Closed Posted

Opportunity number
RFA-MH-27-205
Agency
Applications due
Award size
Up to $5,000,000

Opportunity facts

Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • Other
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute of Mental Health (NIMH) is soliciting a single-source cooperative agreement (U24 activity code) to support the continuation of the Accelerating Medicines Partnership Schizophrenia (AMP SCZ) Data Processing, Analysis, and Coordination Center (DPACC). The DPACC will manage data processing, quality control, and analysis of longitudinal multi-modal biomarker and clinical outcome data collected from over 2,600 study participants at clinical high risk for schizophrenia, coordinate two multisite U01 clinical research networks, and disseminate findings through the AMP SCZ website and NIMH Data Archive. Applicants must be the current Principal Investigator(s) or Program Director(s) from Brigham and Women's Hospital who held the award under RFA-MH-20-341, and clinical trials are not permitted under this NOFO. Applications will be evaluated using standard NIH peer-review criteria including scientific significance, investigator qualifications, innovation, approach, and institutional environment, followed by advisory council review. The application deadline is June 10, 2026, at 5:00 PM local time, with an earliest project start date of December 2026.

NIMH intends to commit $5,000,000 in FY2027 funding for one award with a maximum project period of three years. The DPACC will complete processing and analysis of 24 months of longitudinal data collection and coordinate activities across multiple clinical research sites. All work will be conducted at Brigham and Women's Hospital, with no cost sharing required and all applications subject to standard NIH grants policy requirements and federal cybersecurity standards.

Synopsis

NIMH is announcing its intent to issue a single source cooperative agreement award to Brigham and Women"s Hospital to support continuation of the AMP® SCZ Data Processing, Analysis, and Coordination Center (DPACC). This allows DPACC to complete the processing and analysis of longitudinal multi-modal biomarker and clinical outcome data collected across 24 months.This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Files

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RFA-MH-27-205-Full-Announcement.html HTML file

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