Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research (P50 Clinical Trial Optional)

Open Posted

Opportunity number
PAR-27-127
Agency
Applications due
Award size
Not on record

Opportunity facts

Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • Non-501(c)(3) Nonprofits
  • 501(c)(3) Nonprofits
  • County Governments
  • Public or Indian Housing Auth.
  • Small Businesses
  • Special District Governments
  • Tribal Governments (Federally Recognized)
  • Higher Education Inst. (Private)
  • For Profit Organizations
  • Other
  • City/Township Governments
  • State Governments
  • Higher Education Inst. (Public)
  • Independent School Districts
  • Tribal Organizations (Not Federally Recognized)
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institute of Mental Health seeks applications for the Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research, with applications due May 25, 2028. This program is restricted to multidisciplinary research teams undertaking integrated, collaborative projects that could not be achieved through standard grant mechanisms.

Eligible applicants include higher education institutions (public and private), nonprofits (501(c)(3) and non-501(c)(3)), for-profit organizations, state and local governments, county governments, city and township governments, tribal governments (federally recognized and non-federally recognized), special district governments, independent school districts, and public or Indian housing authorities. Non-domestic entities and foreign components of U.S. organizations are ineligible.

The program funds three primary research objectives: advancing basic brain and behavior research to uncover mechanisms underlying mental disorders; supporting integration and translation of basic and clinical neuroscience research on severe mental illnesses; and advancing understanding of neurobehavioral developmental mechanisms and trajectories of psychopathology beginning in childhood and adolescence. Applications must include a required Overall component and Administrative Core, a minimum of three integrated Projects, and may include up to three optional Research Support Cores. Clinical trials are optional.

Maximum direct costs are $2 million annually over a maximum project period of five years. The Center Director must commit minimum three person-months annually and lead at least one project and the administrative core. Project leaders must commit 1.8 person-months per project annually.

Applications are evaluated through peer review by the Center for Scientific Review based on Significance, Investigator qualifications, Innovation, Approach, and Environment, with additional emphasis on interdisciplinary integration, training opportunities, data sharing to the National Data Archive, and reproducibility. Awards are made based on scientific merit, fund availability, and program relevance.

The Assistance Listing number is 93.242.

Synopsis

This notice of funding opportunity (NOFO) encourages applications for Silvio O. Conte Centers for Basic Neuroscience or Translational Mental Health Research. The National Institute of Mental Health (NIMH) seeks teams of integrative researchers working at different levels of analysis and employing novel, and creative experimental approaches to address high-risk, high-impact questions with the primary objectives of: (a) advancing basic brain and behavior research that will uncover underlying mechanisms that could provide the foundation for understanding mental disorders; (b) supporting the integration and translation of basic and clinical neuroscience research on severe mental illnesses; (c) advancing our understanding of the neurobehavioral mechanisms and trajectories of psychopathology that begin in development. This program is intended only for projects that could not be achieved using other, more standard grant mechanisms.

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Files

File Type Posted
PKG00294099.pdf PDF
PAR-27-127-Full-Announcement.html HTML file

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