Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)

Closed Posted

Opportunity number
RFA-CA-25-005
Agency
Applications due
Award size
Up to $150,000

Opportunity facts

Assistance listings
Funding instrument
Grant
Categories
  • Education
  • Health
Eligible applicants
  • For Profit Organizations
  • Special District Governments
  • Public or Indian Housing Auth.
  • State Governments
  • County Governments
  • Independent School Districts
  • Higher Education Inst. (Public)
  • Tribal Organizations (Not Federally Recognized)
  • Other
  • Non-501(c)(3) Nonprofits
  • City/Township Governments
  • Small Businesses
  • Tribal Governments (Federally Recognized)
  • 501(c)(3) Nonprofits
  • Higher Education Inst. (Private)
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The Department of Health and Human Services National Institutes of Health (NIH) is seeking revision applications from currently funded NCI R01 research projects through the Innovative Molecular Analysis Technologies (IMAT) program. This funding opportunity aims to encourage researchers to expand their original research questions by incorporating new technical approaches or devices developed through NCI support. Eligible applicants include for-profit organizations, state and local governments, tribal organizations, higher education institutions, and nonprofits. The primary objective is to incentivize independent validation and accelerate the adoption of emerging technologies in cancer research. Applicants will be evaluated based on their ability to enhance existing research through interdisciplinary collaboration and innovative tools. The solicitation is open from December 31, 2024, with a proposal submission deadline of December 9, 2025.

While specific award amounts are not explicitly detailed, this opportunity falls under the Cancer Detection and Diagnosis Research program (CFDA 93.394), which historically has funded projects ranging from $200,000 to nearly $3 million. The project periods typically span 2-5 years, with funding focused on advancing cancer screening, detection, diagnosis, and research methodologies. Research will be conducted at the recipient organizations' facilities across the United States, with a strong emphasis on translational research that can potentially improve cancer detection, diagnosis, and patient outcomes. The program supports projects developing novel technologies, diagnostic tools, imaging techniques, and computational methods to enhance early cancer identification and treatment monitoring.

Synopsis

2 versions

Update #2 · Latest ·

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage revision applications (formerly called "competing revisions") from currently funded NCI R01 research projects. The applicants should propose to expand upon the original research question(s) or otherwise accelerate progress for the parent study by incorporating a new technical approach or device developed through support from the NCI Innovative Molecular Analysis Technologies (IMAT) program. Awards from this NOFO are meant to incentivize independent validation and accelerate the adoption of these emerging technologies by appropriate research communities.As a component of the NCI IMAT program, this NOFO aims to promote interdisciplinary collaboration in the development of innovative tools and methods that enable cancer research and accelerate scientific discovery.

Update #1 ·

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage revision applications (formerly called "competing revisions") from currently funded NCI R01 research projects. The applicants should propose to expand upon the original research question(s) or otherwise accelerate progress for the parent study by incorporating a new technical approach or device developed through support from the NCI Innovative Molecular Analysis Technologies (IMAT) program. Awards from this NOFO are meant to incentivize independent validation and accelerate the adoption of these emerging technologies by appropriate research communities. As a component of the NCI IMAT program, this NOFO aims to promote interdisciplinary collaboration in the development of innovative tools and methods that enable cancer research and accelerate scientific discovery.

Files

File Type Posted
RFA-CA-25-005-Full-Announcement.html HTML file

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