Radiation Oncology-Biology Integration Network (ROBIN) Centers (U54 Clinical Trial Required)
Forecasted Federal grant Posted
- Opportunity number
- RFA-CA-27-003
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- Not on record
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Tribal Governments (Federally Recognized)
- County Governments
- State Governments
- Independent School Districts
- Special District Governments
- Public or Indian Housing Auth.
- For Profit Organizations
- Higher Education Inst. (Public)
- Higher Education Inst. (Private)
- City/Township Governments
- Non-501(c)(3) Nonprofits
- Tribal Organizations (Not Federally Recognized)
- 501(c)(3) Nonprofits
- Other
- Small Businesses
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Cancer Institute is soliciting cooperative agreement applications to continue support for the Radiation Oncology-Biology Integration Network (ROBIN) Centers, accepting applications from both new and renewing investigators, though no specific application deadline is provided in this forecast notice.
ROBIN operates as a national collaborative research network structured around multidisciplinary, longitudinal studies designed to understand how tumors and normal tissues change biologically during radiation therapy. The program collects and analyzes biospecimens and multimodal data before, during, and after standard-of-care radiation therapy to reveal mechanisms of response, resistance, and toxicity; identify therapy-induced targets; and determine whether initial tumor profiling strategies remain optimal as therapy progresses. The network integrates expertise in biology, clinical oncology, imaging, dosimetry, omics, biospecimen science, and data science, with the broader objective of accelerating translational discoveries that inform future clinical trials and improve cancer outcomes.
Eligible applicants include higher education institutions (public and private), non-profit organizations, for-profit organizations, state and local government agencies, tribal governments and organizations, housing authorities, and other entity types. The source does not specify award ceilings, floors, expected number of awards, cost-share requirements, period of performance, or place of performance. The opportunity is assigned to CFDA 93.394 (Cancer Detection and Diagnosis Research) and CFDA 93.395 (Cancer Treatment Research). Award decisions will be based on scientific merit, program relevance, program balance, and alignment with NCI and NIH strategic priorities, with applications reviewed competitively on renewal.
Forecast synopsis
Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) intends to continue to support the Radiation Oncology-Biology Integration Network (ROBIN) with applications from both new and renewing investigators. This network model will sustain an agile and effective national radiation oncology infrastructure that collectively addresses critical hypothesis-based translational research on the biological basis of responses in cancer patients who undergo radiation treatments. ROBIN supports a collaborative national research network focused on understanding how tumors and normal tissues change biologically during radiation therapy. Because radiation can dynamically alter molecular targets over the course of treatment, the network seeks to generate foundational knowledge that can improve radiation-based cancer care and identify new opportunities for combining radiation with drugs and other therapies. Through multidisciplinary, longitudinal studies, ROBIN centers collect and analyze biospecimens and multimodal data before, during, and after standard-of-care radiation therapy. This work is designed to reveal mechanisms of response, resistance, and toxicity; identify new therapy-induced targets; and determine whether treatment strategies based on initial tumor profiling remain optimal as therapy progresses. The network also strengthens the radiation oncology workforce by integrating expertise in biology, clinical oncology, imaging, dosimetry, omics, biospecimen science, and data science. By sustaining this research infrastructure, NIH aims to accelerate translational discoveries that can inform future clinical trials and improve outcomes for people with cancer.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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