NIAID Investigator Initiated Program Project Applications (P01 Clinical Trial Not Allowed)
Open Posted
- Opportunity number
- PAR-27-082
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications due
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- Special District Governments
- Tribal Governments (Federally Recognized)
- Higher Education Inst. (Private)
- Higher Education Inst. (Public)
- For Profit Organizations
- Tribal Organizations (Not Federally Recognized)
- Small Businesses
- State Governments
- 501(c)(3) Nonprofits
- City/Township Governments
- Independent School Districts
- Other
- Non-501(c)(3) Nonprofits
- County Governments
- Public or Indian Housing Auth.
- Points of contact
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institute of Allergy and Infectious Diseases (NIAID) seeks investigator-initiated Program Project (P01) applications addressing infectious disease biology, host-microbe interactions, immune system mechanisms, immune dysfunction disorders, and translational research for vaccines, therapeutics, and diagnostics, with applications due May 25, 2029. Clinical trials are not allowed.
Eligible applicants include higher education institutions (public and private), nonprofits with or without 501(c)(3) status, for-profit organizations, state and local governments, Indian tribal governments, and public or Indian housing authorities. Foreign organizations and non-domestic components of U.S. organizations are ineligible; foreign components of U.S. organizations are allowed.
Each application must include a minimum of two synergistic Research Projects sharing a common central theme and an Administrative Core; Scientific Core(s) are optional. Award budgets are not limited and must reflect actual project needs, with maximum project periods of five years. The program offers staggered application windows throughout 2026–2029 (September 25, 2026; January 25, 2027; May 25, 2027; and continuing quarterly thereafter), with peer review occurring 3–4 months after submission and earliest start dates ranging from July 2027 through February 2030.
Peer review by Scientific Review Groups evaluates significance, investigator qualifications, innovation, approach, and environment. Prior consultation with NIAID staff at least 15 weeks before the due date is strongly encouraged. Applicants must maintain active registrations in System for Award Management (SAM), obtain a Unique Entity Identifier (UEI), register with eRA Commons, and complete Grants.gov registration. All Program Directors/Principal Investigators must have eRA Commons accounts linked to valid ORCID IDs. Assistance Listing 93.855.
Synopsis
This notice of funding opportunity (NOFO) invites submission of investigator-initiated Program Project (P01) applications. The proposed Programs should address scientific areas relevant to the NIAID mission including: biology and pathogenesis of infectious microbes, including HIV; host-microbe interactions; mechanisms regulating immune system development and function across the lifespan, and in response to infectious pathogens; immune dysfunction resulting in allergy, asthma, autoimmunity, immunodeficiency, or transplant rejection; and translational research to develop vaccines, therapeutics, and diagnostics to prevent and treat infectious and immune-mediated diseases. Each application submitted to this NOFO must include at least two related, synergistic Research Projects that share a common central theme, focus, and/or overall objective; and an Administrative Core. An application may include Scientific Core(s), if needed for the proposed research.
Eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organization) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Files
| File | Type | Posted |
|---|---|---|
| PKG00292715.pdf | ||
| PAR-27-082-Full-Announcement.html | HTML file |
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