NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required)

Closed Posted

Opportunity number
RFA-CA-27-006
Agency
Applications due
Award size
Not on record

Opportunity facts

Assistance listings
Funding instrument
Cooperative Agreement
Category
  • Health
Eligible applicants
  • For Profit Organizations
  • Special District Governments
  • Small Businesses
  • Independent School Districts
  • State Governments
  • Public or Indian Housing Auth.
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Public)
  • Higher Education Inst. (Private)
  • County Governments
  • 501(c)(3) Nonprofits
  • Other
  • Tribal Organizations (Not Federally Recognized)
  • Tribal Governments (Federally Recognized)
  • City/Township Governments

Opportunity details come from Grants.gov. Updated .

About this opportunity

Written by GovTribe AI ·

The National Cancer Institute seeks applicants for the NCORP Research Bases cooperative agreement program by September 18, 2026, intending to commit $74.5 million to fund up to seven awards with a 6-year project period. Eligible applicants are limited to NCI Clinical Trials Network (NCTN) Groups, cancer foundations affiliated with NCTN Groups, or NCI-designated Cancer Centers with comprehensive cancer clinical research expertise. Foreign organizations and non-domestic components of U.S. organizations are not eligible; foreign components as defined in the NIH Grants Policy Statement are allowed.

Research Bases must serve as research hubs for the NCORP network, providing established organizational structure with scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery (CCP & CD) clinical research as well as quality-of-life studies embedded within treatment and imaging studies. Bases assume responsibility for study operations and data management, including protocol development, FDA and Office of Human Research Protections compliance, auditing, training, quality assurance, and support to Community Sites and Minority/Underserved Community Sites. Applications must propose clinical trials and include a minimum 1.2 person-months per year effort commitment from each PD/PI. Applicants must address one or more of three research areas: Cancer Control Research (required), Cancer Prevention Research (optional), and Cancer Care Delivery Research (optional), integrating health disparities across all focus areas as appropriate.

Budget requirements include annual travel funds for four persons to attend one NCORP meeting yearly and per-case management funding for member sites ranging from $650 to $3,300 per patient depending on trial type. Peer review and advisory council review occur by March 2027, with earliest start date of September 18, 2027. Applications are evaluated on significance, investigator qualifications, innovation, approach, and environment, with emphasis on addressing critical gaps in cancer prevention and control and capability to conduct multi-institutional trials. CFDA numbers are 93.393 and 93.399.

Synopsis

This Notice of Funding Opportunity (NOFO) is one of three NOFOs for the National Cancer Institute (NCI) Community Oncology Research Program (NCORP). NCORP is designed to enhance generalizability and dissemination of clinical trial and other human subject research study results through accrual in a variety of community settings. The purpose of NCORP is to engage cancer patient populations, those at risk of cancer, and organizations in rigorous studies focused on cancer control, prevention, treatment and care delivery.NCORP is a community-based research network that:Designs and conducts clinical trials and other human subject studies for adults and children in cancer control, prevention, screening, and care delivery, as well as quality-of-life studies embedded within treatment trials;Enhances patient and provider access to treatment and imaging trials conducted under the National Clinical Trials Network (NCTN);NCORP will support the following components that will be individually awarded through the respective Request for Applications (RFAs) indicated below:NCORP Research Bases (UG1 Clinical Trials Required)(covered by this NOFO);NCORP Community Sites (UG1 Clinical Trials Not Allowed); andNCORP Academic Community Sites (UG1 Clinical Trials Not Allowed).NCORP Research Bases will serve as the program's research hubs and are expected to:Provide an established organizational structure, with scientific and statistical leadership for developing, implementing, and analyzing multi-institutional cancer control, prevention, and care delivery (CCP & CD) clinical research, as well as quality-of-life studies embedded in treatment and imaging studies.Assume responsibility for study operations and data management, including efficient protocol development; compliance with Food and Drug Administration (FDA) and Office of Human Research Protections (OHRP) regulatory and participant protection requirements; auditing; training; quality assurance; and support to Community Sites and Academic Community Sites.Be based at institutions with comprehensive cancer clinical research expertise (e.g., NCI-designated Cancer Center, or healthcare research organization - including NCI's National Clinical Trials Network (NCTN) Group Operations Centers, or a cancer foundation associated with a NCTN Group).

Eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Files

File Type Posted
PKG00292876.pdf PDF
RFA-CA-27-006-Full-Announcement.html HTML file

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