National Biomedical Research Centers (P50 Clinical Trial Optional)
Forecasted Federal grant Posted
- Opportunity number
- PAR-28-017
- Agency
-
National Institutes of Health
Department of Health and Human Services
- Applications expected due
- Award size
- $7,955,376 to $11,405,967
Opportunity facts
- Expected posting
- Assistance listings
- Funding instrument
- Grant
- Category
-
- Health
- Eligible applicants
-
- Tribal Organizations (Not Federally Recognized)
- Special District Governments
- Tribal Governments (Federally Recognized)
- State Governments
- Other
- City/Township Governments
- For Profit Organizations
- 501(c)(3) Nonprofits
- Higher Education Inst. (Private)
- County Governments
- Independent School Districts
- Public or Indian Housing Auth.
- Higher Education Inst. (Public)
- Non-501(c)(3) Nonprofits
- Small Businesses
- Points of contact
-
- Oleg Mirochnitchenko oripdcm@mail.nih.gov (301) 435-0744
Opportunity details come from Grants.gov. Updated .
About this opportunity
The National Institutes of Health is soliciting applications for the National Biomedical Research Centers (P50 Clinical Trial Optional) grant program under CFDA 93.351 (Research Infrastructure Programs), with no hard deadline specified in the forecast. Eligible applicants include higher education institutions (public and private), nonprofit organizations (501(c)(3) and non-501(c)(3)), for-profit organizations, state and local governments, tribal governments (federally and non-federally recognized), faith-based and community-based organizations, regional organizations, Indian/Native American tribal governments, eligible federal agencies, U.S. territories or possessions, and non-domestic entities.
This NOFO emphasizes development of innovative human-based models and new technologies to reduce reliance on live research models. Applications must describe clear, actionable plans to reduce, refine, and replace whole-animal use by developing complementary and alternative approaches. The NBRCs will function as centers of innovation in fundamental science and translational hubs that develop, refine, and test novel interventions for clinical use. NIH intends for the NBRCs to become leaders in development and use of human-based approaches, including sophisticated in vitro and in silico models known as New Approach Methodologies (NAMs). Clinical trials are allowed only as human-based NAMs where applicable.
This open competition aims to increase opportunities for innovation, including NAMs research, at research centers with existing nonhuman primate colonies and to further leverage existing capabilities in basic and translational research.
Evaluation criteria include scientific merit and significance of proposed objectives; technical adequacy of experimental design and approach; investigator competency; adequacy of available and proposed facilities and resources; budget necessity in relation to the proposed project; and relevance and importance to announced program objectives.
No award ceiling, floor, or number of expected awards appears in the source material.
Forecast synopsis
The National Biomedical Research Centers (NBRCs) are expected to provide scientific expertise, advanced equipment, infrastructure, and a range of well-characterized research models to researchers across the nation. Research at the NBRCs is supported by almost all NIH Institutes, as well as other federal agencies, including those that safeguard US national security interests. This NOFO emphasizes development of innovative human-based models and new technologies to reduce reliance on live research models. Applications must describe clear, actionable plans to reduce, refine, and replace whole-animal use by developing complementary and alternative approaches tailored to relevant use cases in biomedical research. Scientifically, the NBRCs function as centers of innovation in fundamental science as well as translational hubs that develop, refine, and test novel interventions for ultimate use in human patients. It is NIH's intention that the NBRCs become leaders in the development and use of human-based approaches, including sophisticated in vitro and in silico models, known as New Approach Methodologies (NAMs). Clinical trials are allowed only as human-based NAMs, where applicable. This notice of funding opportunity (NOFO) is an open competition to increase opportunities for innovation, including NAMs research, at research centers with existing nonhuman primate colonies, and to further leverage existing capabilities in basic and translational research.
Eligibility
Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
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