Multi-Site Study of the Health Implications of Exposure to PFAS-Contaminated Drinking Water
Closed Posted
- Opportunity number
- RFA-TS-19-002
- Applications due
- Originally
- Award size
- Not on record
Opportunity facts
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Health
- Eligible applicants
-
- Public or Indian Housing Auth.
- Non-501(c)(3) Nonprofits
- Unrestricted
- Special District Governments
- Higher Education Inst. (Private)
- 501(c)(3) Nonprofits
- County Governments
- For Profit Organizations
- Independent School Districts
- Tribal Governments (Federally Recognized)
- City/Township Governments
- Tribal Organizations (Not Federally Recognized)
- State Governments
- Higher Education Inst. (Public)
- Small Businesses
Opportunity details come from Grants.gov. Updated .
Synopsis
2 versions
Update #2 · Latest ·
The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration.Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated.ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO.
Update #1 ·
The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting research to commence a multi-site study on the human health effects of exposures to drinking water contaminated with per- and polyfluoroalkyl substances (PFAS). Proposed study sites must include communities using PFAS-contaminated private residential wells or public water systems. Exposure assessment will be based on measured PFAS serum levels as well as estimated PFAS serum levels derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time. Specifically, grant awardees will be required to conduct historical reconstruction/water modeling in order to determine the PFAS concentration. Effect biomarkers such as lipids and tests of immune and thyroid function derived from pharmacokinetic modeling of reconstructed PFAS drinking water concentrations over time will be evaluated. ATSDR intends this research to be a two-part program consisting of (1) a mandatory core research protocol to allow ATSDR to aggregate the core data and to compare laboratory and statistical analyses across sites, and (2) each successful awardee will have the option to propose additional investigator-initiated research questions and hypotheses related to the overall goals of this NOFO.
Files
| File | Type | Posted |
|---|---|---|
| RFA-TS-19-002 Revised 05 31 19.pdf | ||
| RFA-TS-19-002 Revised.pdf | ||
| RFA-TS-19-002.pdf | ||
| RFA-TS-19-002.pdf | ||
| PKG00249584-instructions.pdf |
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