Mitigating Proliferation Risks Posed by Artificial Intelligence Enabled Molecular Models and Leveraging Nonproliferation Opportunities
Closed Posted
- Opportunity number
- DFOP0018449
- Agency
-
Department of State
- Applications due
- Award size
- Up to $4,000,000
Opportunity facts
- Assistance listings
- Funding instrument
- Cooperative Agreement
- Category
-
- Science and Technology and other Research and Development
- Eligible applicants
-
- Other
- Higher Education Inst. (Private)
- Small Businesses
- Higher Education Inst. (Public)
- 501(c)(3) Nonprofits
- For Profit Organizations
- Non-501(c)(3) Nonprofits
- Points of contact
- Full announcement
Opportunity details come from Grants.gov. Updated .
About this opportunity
The Department of State's Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is soliciting applications for cooperative agreements to develop safeguards countering misuse risks from proliferation of chemical and biological artificial intelligence models (CBAIMs), with proposals due July 21, 2026 at 11:59 p.m.
Eligible applicants include domestic nonprofit organizations, nonprofit NGOs, educational institutions (public and private), small businesses, for-profit organizations, and 501(c)(3) nonprofits. The NOFO does not specify mandatory cost share or matching requirements. Total funding availability and individual award amounts are not stated in the source; proposals may not exceed the total availability of funds under this NOFO. The source does not specify the expected number of awards or a period of performance.
ACN/NDF welcomes proposals addressing all or a clearly articulated, targeted subset of the key objectives outlined in the line of effort (Section II of the full solicitation). Applicants must indicate whether the proposal involves collaboration with a partner organization separately responding to this solicitation. The funding activity category is classified as Science and Technology and other Research and Development.
The assistance is awarded under CFDA 19.224 (Nonproliferation and Disarmament Fund), administered by the Department of State Bureau of International Security and Nonproliferation. This program supports rapid-response funding for nonproliferation and disarmament initiatives addressing biological, chemical, radiological, and nuclear threat domains through international capacity building, technical assistance, training, and policy implementation. Recent awards under this program have ranged from approximately $51,000 to $5.9 million with performance periods of 12 to 48 months.
Required submissions include project proposal, budget detail, budget narrative, key personnel documentation, and performance indicators. An FAQ document was posted June 29, 2026.
Synopsis
2 versions
Update #2 · Latest ·
The Department of State's Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ACN/NDF invites domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDF's efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the proliferation of chemical and biological Artificial Intelligence (AI) models (CBAIMs). Proposals may not exceed the total availability of funds under this NOFO. ACN/NDF welcomes proposals that fully address all or a clearly articulated, targeted subset of the key objectives of this NDF line of effort (Section II). Please indicate whether the proposal involves collaboration with a partner organization that is separately responding to this solicitation.
Update #1 ·
The Department of State's Office of the Nonproliferation and Disarmament Fund (ACN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ACN/NDF invites domestic non-profit/non-governmental organizations, educational institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDF's efforts to identify, evaluate, and develop safeguards to counter the misuse risks enabled by the proliferation of chemical and biological Artificial Intelligence (AI) models (CBAIMs). Proposals may not exceed the total availability of funds under this NOFO. ACN/NDF welcomes proposals that fully address all or a clearly articulated, targeted subset of the key objectives of this NDF line of effort (Section II). Please indicate whether the proposal involves collaboration with a partner organization that is separately responding to this solicitation.
Files
| File | Type | Posted |
|---|---|---|
| FY26 NDF Project Proposal Template.docx | DOCX document | |
| Budget Detail & Budget Summary - TEMPLATE.xlsx | XLSX spreadsheet | |
| Budget Narrative Template.docx | DOCX document | |
| Key Personnel Document.docx | DOCX document | |
| NOFO Sample Performance Indicators Template.xlsx | XLSX spreadsheet | |
| DFOP0018449 Solicitation.pdf | ||
| DFOP0018449 FAQ 6.29.2026.pdf |
Posting history
| Listing | Posted | Applications due |
|---|---|---|
| Opportunity | ||
| Opportunity |
On GovTribe
Work this opportunity
- Track it in your pipeline
- Find teaming partners
- Similar grant opportunities
- Ask GovTribe AI about this opportunity