Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)

Forecasted Federal grant Posted

Opportunity number
RFA-ES-27-009
Agency
Applications expected due
Award size
$100,000 to $500,000

Opportunity facts

Expected posting
Assistance listings
Funding instrument
Grant
Category
  • Health
Eligible applicants
  • City/Township Governments
  • For Profit Organizations
  • State Governments
  • Public or Indian Housing Auth.
  • Other
  • Higher Education Inst. (Public)
  • 501(c)(3) Nonprofits
  • Independent School Districts
  • Special District Governments
  • Small Businesses
  • Tribal Organizations (Not Federally Recognized)
  • County Governments
  • Non-501(c)(3) Nonprofits
  • Higher Education Inst. (Private)
  • Tribal Governments (Federally Recognized)
Points of contact

Opportunity details come from Grants.gov. Updated .

About this opportunity

Written by GovTribe AI ·

The National Institutes of Health is forecasting grant awards to support mechanistic research on how exposure to metals and metal-containing compounds alters biological processes relevant to human health. This is a forecast announcement with no application due date specified in the source. Clinical trials (RP1) are not allowed under this funding opportunity.

Eligible applicants include higher education institutions (public and private), 501(c)(3) and non-501(c)(3) nonprofits, for-profit organizations, small businesses, state and local governments, county and tribal governments (federally recognized and other), special district governments, independent school districts, public or Indian housing authorities, U.S. territories or possessions, faith-based or community-based organizations, eligible federal agencies, and regional organizations.

The program prioritizes studies that elucidate absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals, including mechanisms through which metals may alter immune homeostasis, cross the placental barrier, or gain access to and affect the central nervous system. Research may employ experimental models, new approach methodologies, computational approaches, or leverage human biospecimens to address defined mechanistic hypotheses.

Awards are made under CFDA 93.113 (Environmental Health) through the National Institute of Environmental Health Sciences. Recent research project grants under this program typically range from $200 thousand to $800 thousand, with individual awards ranging from $30 thousand to $3.8 million. Dual review occurs at the study section level and through a national advisory council. Evaluation criteria include scientific merit, technical adequacy of experimental design, investigator competency, facility adequacy, budget necessity, and relevance to program objectives.

Forecast synopsis

The purpose of this funding opportunity is to support mechanistic research to understand how exposure to metals and metal-containing compounds alters biological processes relevant to human health. Of particular interest are studies that elucidate the absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals, including mechanisms through which metals may alter immune homeostasis, cross the placental barrier, or gain access to and affect the central nervous system. Studies may employ experimental models, new approach methodologies, computational approaches, or leverage human biospecimens where these approaches are used to address defined mechanistic hypotheses.

Eligibility

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

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