Mechanistic links between diet, lipid metabolism, and tumor growth and progression (UH2 Clinical Trial Not Allowed)

Closed Posted

Opportunity number
PAR-25-118
Agency
Applications due
Award size
Not on record

Opportunity facts

Funding instrument
Cooperative Agreement
Categories
  • Education
  • Health
Eligible applicants
  • Special District Governments
  • Other
  • Higher Education Inst. (Private)
  • Small Businesses
  • County Governments
  • Tribal Governments (Federally Recognized)
  • Non-501(c)(3) Nonprofits
  • 501(c)(3) Nonprofits
  • For Profit Organizations
  • City/Township Governments
  • Public or Indian Housing Auth.
  • Higher Education Inst. (Public)
  • Independent School Districts
  • Tribal Organizations (Not Federally Recognized)
  • State Governments
Points of contact
Full announcement

Opportunity details come from Grants.gov. Updated .

About this opportunity

The National Institutes of Health (NIH) is seeking mechanistic research proposals investigating the links between diet, lipid metabolism, and tumor growth and progression through this Notice of Funding Opportunity (NOFO). The cooperative agreement grant aims to support fundamental studies that identify molecular mechanisms through which lipid metabolism mediates cancer development, with a specific focus on bridging nutrition and molecular metabolism research. Eligible applicants include universities, nonprofits, small businesses, tribal organizations, and government entities across multiple sectors. Proposals will be evaluated based on scientific merit, experimental design, investigator competence, available resources, budget appropriateness, and relevance to program objectives. The application deadline is December 9, 2025, and unpublished preliminary data is limited to one half-page figure to encourage new investigator participation.

The grant will be awarded as a cooperative agreement through the Department of Health and Human Services' National Institutes of Health, specifically targeting cancer-related research programs including Cancer Detection and Diagnosis Research (CFDA 93.394), Cancer Treatment Research (CFDA 93.395), and Cancer Biology Research (CFDA 93.396). While specific award amounts are not detailed in the documentation, NIH cancer research grants typically range from $200,000 to $3 million, with project periods spanning 2-5 years. Research will be conducted at the recipient's facilities, with an emphasis on developing innovative tools and approaches to understanding the complex interactions between diet, lipid metabolism, and cancer progression.

Synopsis

Through this Notice of Funding Opportunity (NOFO) is to request applications that propose mechanistic investigations of the links between diet, lipid metabolism and tumor growth and progression. It is anticipated that this program will support fundamental studies designed to identify and define the molecular mechanisms through which lipid metabolism mediates tumor growth and progression, focusing specifically on the central role lipids play in linking diet with the biology of cancer; bridge the historically divided fields of nutrition and molecular metabolism; and stimulate research and tool development in this emerging area, which faces particular challenges because of the complexity of lipid biochemistry. For this announcement, unpublished preliminary data are limited to one figure, comprising no more than one-half page, to facilitate the entry of qualified new investigators to the field.

Files

File Type Posted
PAR-25-118-Full-Announcement.html HTML file

On GovTribe

Work this opportunity

  • Track it in your pipeline
  • Find teaming partners
  • Similar grant opportunities
  • Ask GovTribe AI about this opportunity